Deatailed information for cohesin site CDBP00417655

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  • Basic information
  • CohesinDB ID: CDBP00417655
  • Locus: chr21-34185935-34187049
  • Data sourse: ENCSR000BTQ, GSE67783, GSE86191, GSE72082, GSE98367, GSE206145, GSE206145-NatGen2015, ENCSR153HNT
  • Cell type: MCF-7, RPE, Fibroblast, HCT-116, Hep-G2, K-562, HSPC, Macrophage
  • DNA Sequence of binding site: UCSC hg38
  • Cohesin category
  • Peak occupancy ratio: 2% samples have this site.
  • Cell specificity (0: conserved, 1: cell type specific): 0.911
  • Subunit: Mau2,SA1,Rad21,SMC1
  • CTCF binding site: CTCF CTCF motif: False
  • Genomic location: TES
  • 3D genome
  • TAD boundary: non-Boundary
  • Chromatin hubs: non-Hub
  • Hi-C loops: True Hi-ChIP loops: True ChIA-PET loops: True
  • Compartment: 91% Hi-C samples shows Compartment A
  • Cis-regulatory elements
  • Enhancer (Fantom5): non-Enhancer
  • Super enhancer (SEdb): True
  • Chromatin annotation: "15_Quies": 62%, "5_TxWk": 21%,
    Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
  • Co-bound Transcriptional factors: NFIA, FOSL1, PGR, FOXA1, PBX2, RXRB, ATF3, MXD4, SMARCE1, MITF, CDX2, TRIM28, NFE2L2, LMO2, ESR1, OCA2, CTCF, TCF12, JUN, EP300, MNT, ZNF157, GATA6, DPF2, E2F6, TRIM24, SOX6, E2F4, TEAD4, FOXA3, GATAD2A, TFAP2C, POU2F2, ZNF263, BRD3, MYCN, ID3, CTBP1, ZBTB48, ZSCAN5A, NONO, DDX5, NBN, MYC, SMARCA4, ARID1B, RAD21, XRCC5, LEF1, RCOR1, NFE2, NR2F6, EZH2, EBF3, GABPB1, HDAC2, GATA2, ZNF644, MXD3, HCFC1, NR2C2, NCOA2, ZNF554, ATF1, ETV5, THAP11, MAFG, SMC1A, HDAC1, EZH2phosphoT487, CBX1, SIN3A, ZFX, SOX13, ZNF770, TWIST1, CREBBP, RARA, RUNX2, GATA4, PRDM9, HMBOX1, SMAD4, ZEB2, CBFA2T3, NR2C1, FOS, MED1, TEAD3, CEBPD, ZNF3, L3MBTL2, SETDB1, USF1, NIPBL, MAFK, BCL11A, GSPT2, IKZF5, ATF7, BCOR, SMC3, STAG1, PAX7, CBX3, MTA3, CREM, FOXA2, ZNF692, WT1, MAFF, ZNF580, RELA, NEUROD1, JUNB, ISL1, ZFP36, SKIL, OTX2, GATA3, MGA, TAL1, MAX, NRIP1, ZNF143, GATA1, HAND2, PLAG1, NCOA3, NR2F2, NR2F1, KDM5B, ZNF334, MYOD1, PHOX2B, T, BRD2, BHLHE40, AR, TAF1, RXR, EGLN2, EGR1, ZBTB26, RNF2, MYNN, BRD4, JUND, SCRT1, MAZ, TBX2, AHR, FOSL2
  • Target gene symbol (double-evidenced CRMs): ITSN1,RCAN1,MRPS6,SLC5A3,AP000311.1,ATP5PO
  • Function elements
  • Human SNPs: .
  • Number of somatic mutations (coding): 0
  • Number of somatic mutations (non-coding): 6
  • Related genes and loops
  • Related gene: ENSG00000249209, ENSG00000205726, ENSG00000241837, ENSG00000243927, ENSG00000198743, ENSG00000159200,
  • Related loop: chr21:33900000-33925000~~chr21:34175000-34200000, chr21:34075000-34100000~~chr21:34175000-34200000, chr21:34175000-34200000~~chr21:34325000-34350000, chr21:34175000-34200000~~chr21:34500000-34525000,
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