Deatailed information for cohesin site CDBP00417658

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  • Basic information
  • CohesinDB ID: CDBP00417658
  • Locus: chr21-34191993-34192521
  • Data sourse: GSE206145-NatGen2015, ENCSR153HNT, GSE83726
  • Cell type: K-562, Fibroblast, RH4
  • DNA Sequence of binding site: UCSC hg38
  • Cohesin category
  • Peak occupancy ratio: 1% samples have this site.
  • Cell specificity (0: conserved, 1: cell type specific): 0.967
  • Subunit: SA1,Rad21
  • CTCF binding site: non-CTCF CTCF motif: False
  • Genomic location: TES
  • 3D genome
  • TAD boundary: non-Boundary
  • Chromatin hubs: non-Hub
  • Hi-C loops: True Hi-ChIP loops: True ChIA-PET loops: True
  • Compartment: 91% Hi-C samples shows Compartment A
  • Cis-regulatory elements
  • Enhancer (Fantom5): non-Enhancer
  • Super enhancer (SEdb): True
  • Chromatin annotation: "15_Quies": 67%, "5_TxWk": 21%,
    Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
  • Co-bound Transcriptional factors: FOXO1, FOSL1, CBX5, MEIS2, FOXA1, RBFOX2, PBX2, ZFHX2, ATF3, NFIC, ATF4, SMARCE1, HDAC3, TEAD1, TRIM28, NFE2L2, RCOR2, ESR1, OCA2, JUN, TCF12, CTCF, EP300, E4F1, MNT, GATA6, SOX5, DPF2, TRIM24, SOX6, E2F1, TEAD4, FOXA3, ZNF175, GATAD2A, EHMT2, TFAP2C, POU2F2, ID3, CTBP1, MTA2, ZNF317, DUX4, SAP130, NBN, ARID3A, ERG2, ERG, SMARCC2, MYC, SMARCA4, ARID1B, RAD21, HOMEZ, FOXK2, GABPA, XRCC5, IKZF1, RCOR1, NFE2, LEF1, NR2F6, MIER3, ARNTL, NR3C1, CEBPB, ESRRA, CREB1, TBL1XR1, BMPR1A, SPI1, HES1, MIXL1, IRF1, HDAC2, GATA2, HCFC1, NR2C2, HEXIM1-CDK9, EP400, ATF1, CC2D1A, THAP11, MAFG, CBX1, CEBPA, HDAC1, CRY1, SOX13, ZFX, ERG3, ZMIZ1, ZNF35, GATA4, ARNT, ZEB2, NFYA, HMBOX1, CBFA2T3, FOXM1, NR2C1, FOS, CDK8, GMEB1, TEAD3, PML, DIDO1, MYB, CEBPD, C11orf30, L3MBTL2, NCOA1, SETDB1, STAT5A, KLF16, MAFK, NR4A1, REST, ZBTB7A, ZNF479, CCNT2, ATF7, AFF1, MBD2, FOXP1, BCOR, MLLT1, CBFA2T2, ZNF316, FOXA2, MTA3, CBX3, CREM, MIER2, ZBED1, ZNF30, MAFF, WT1, ZNF318, KDM1A, YY1, RELA, CREB3L1, TARDBP, ZNF589, NEUROD1, JUNB, ZNF148, ZNF282, ZNF830, ZFP36, SKIL, OTX2, GATA3, MGA, TAL1, MAX, ZNF143, MTA1, GATA1, CEBPG, ZNF592, GFI1B, NR2F2, NCOA3, NR2F1, NEUROG2, PKNOX1, ZNF334, MYOD1, EGR2, BRD2, BHLHE40, AR, ZBTB40, EGR1, ZBTB26, RNF2, NCOR1, JUND, ILF3, BRD4, CUX1, MAZ, MEF2D, ZNF24, AHR, FOSL2
  • Target gene symbol (double-evidenced CRMs): SLC5A3,AP000311.1,RCAN1,ATP5PO,ITSN1,MRPS6
  • Function elements
  • Human SNPs: .
  • Number of somatic mutations (coding): 0
  • Number of somatic mutations (non-coding): 1
  • Related genes and loops
  • Related gene: ENSG00000249209, ENSG00000205726, ENSG00000241837, ENSG00000243927, ENSG00000198743, ENSG00000159200,
  • Related loop: chr21:33900000-33925000~~chr21:34175000-34200000, chr21:34075000-34100000~~chr21:34175000-34200000, chr21:34175000-34200000~~chr21:34325000-34350000, chr21:34175000-34200000~~chr21:34500000-34525000,
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