- Basic information
- CohesinDB ID: CDBP00417674
- Locus: chr21-34231432-34232119
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Data sourse: ENCSR000BLD, ENCSR230ZWH, GSE72082, ENCSR000BSB, ENCSR000BLY, GSE105028, GSE103477, GSE25021, ENCSR000EDW, ENCSR917QNE, GSE93080, ENCSR000DZP, ENCSR000EAC, GSE143937, ENCSR000BKV, GSE67783, GSE86191, GSE76893, GSE206145-NatGen2015, ENCSR703TNG, GSE116344, GSE98367, ENCSR879KXD, ENCSR000BLS, GSE206145, ENCSR000ECE, ENCSR000BMY, ENCSR000EHX, GSE97394, ENCSR000BTQ, ENCSR167MTG, GSE129526, ENCSR054FKH, ENCSR153HNT, GSE50893, GSE126755
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Cell type: MDM, RH4, GM10847, GM2610, GM19240, HSPC, Liver, H9-hESC, RPE, GM2630, Fibroblast, GM12890, GM2255, K-562, GM18486, GM18526, H1-hESC, SNYDER, GM18505, GM12878, GM12891, GM2588, SK-N-SH, GM19239, GM19193, Macrophage, HUES64, MCF-7, GM12892, HCT-116, Hep-G2, GM19238, Neutrophil, GM18951
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 17% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.622
- Subunit: SA1,Rad21,SMC1,SA2,SMC3
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CTCF binding site: CTCF
CTCF motif: False
- Genomic location: Intragenic
- 3D genome
- TAD boundary: non-Boundary
- Chromatin hubs: Hub
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Hi-C loops: True
Hi-ChIP loops: True
ChIA-PET loops: True
- Compartment:
91% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): False
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Chromatin annotation:
"15_Quies": 74%,
"14_ReprPCWk": 17%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: POU2F2, SMC1A, SIN3A, ZFX, CTBP1, ZBTB48, ZNF205, ZNF574, SUZ12, PBX2, RELA, ZBTB2, MYC, CDK6, RAD21, SP140, GRHL3, ZFP36, ZNF48, MAX, GATA1, CDK8, RCOR1, HAND2, SCRT2, OCA2, USF2, CTCF, REST, BRD4, SCRT1, ZNF766, MAZ, SMC3, STAG1
- Target gene symbol (double-evidenced CRMs): ATP5PO,ITSN1,RCAN1,MRPS6,AP000311.1
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 0
- Number of somatic mutations (non-coding): 0
- Related genes and loops
- Related gene:
ENSG00000249209,
ENSG00000205726,
ENSG00000241837,
ENSG00000243927,
ENSG00000159200,
- Related loop:
chr21:33900000-33925000~~chr21:34225000-34250000,
chr21:33922506-33925702~~chr21:34231067-34232322,
chr21:33922678-33925692~~chr21:34230884-34232496,
chr21:33922803-33925652~~chr21:34230934-34232390,
chr21:33922807-33925639~~chr21:34230926-34232381,
chr21:33923163-33925652~~chr21:34230928-34232534,
chr21:33923273-33925677~~chr21:34231086-34232306,
chr21:33923351-33925672~~chr21:34231078-34232324,
chr21:33925000-33950000~~chr21:34225000-34250000,
chr21:34125000-34150000~~chr21:34225000-34250000,
chr21:34225000-34250000~~chr21:34325000-34350000,
chr21:34225000-34250000~~chr21:34500000-34525000,
chr21:7750000-7775000~~chr21:34225000-34250000,