- Basic information
- CohesinDB ID: CDBP00417677
- Locus: chr21-34241424-34241738
-
Data sourse: GSE206145, GSE206145-NatGen2015
-
Cell type: RPE, Fibroblast
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 1% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.978
- Subunit: SA1,Rad21
-
CTCF binding site: CTCF
CTCF motif: False
- Genomic location: Intragenic
- 3D genome
- TAD boundary: non-Boundary
- Chromatin hubs: Hub
-
Hi-C loops: True
Hi-ChIP loops: True
ChIA-PET loops: True
- Compartment:
91% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): False
-
Chromatin annotation:
"15_Quies": 87%,
"14_ReprPCWk": 12%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: RELA, RUNX1, CEBPB, CEBPA, CDK6, GTF2B, ZNF652, CDK8, ERG
- Target gene symbol (double-evidenced CRMs): MRPS6,ITSN1,ATP5PO,RCAN1,AP000311.1
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 0
- Number of somatic mutations (non-coding): 0
- Related genes and loops
- Related gene:
ENSG00000249209,
ENSG00000205726,
ENSG00000241837,
ENSG00000243927,
ENSG00000159200,
- Related loop:
chr21:33900000-33925000~~chr21:34225000-34250000,
chr21:33922474-33925874~~chr21:34242616-34244890,
chr21:33922478-33925703~~chr21:34242552-34244759,
chr21:33922482-33925641~~chr21:34242769-34244742,
chr21:33922485-33925689~~chr21:34242598-34244771,
chr21:33922491-33925917~~chr21:34242559-34244950,
chr21:33922497-33925632~~chr21:34242565-34244736,
chr21:33922506-33925702~~chr21:34243018-34244439,
chr21:33922677-33925654~~chr21:34242517-34244715,
chr21:33922678-33925692~~chr21:34242813-34244834,
chr21:33922723-33925649~~chr21:34242578-34244694,
chr21:33922731-33925983~~chr21:34242565-34244760,
chr21:33922774-33925646~~chr21:34243082-34244282,
chr21:33922794-33925655~~chr21:34242558-34244863,
chr21:33922795-33925611~~chr21:34243084-34244434,
chr21:33922795-33925867~~chr21:34242537-34244933,
chr21:33922803-33925652~~chr21:34243116-34244483,
chr21:33922807-33925639~~chr21:34242597-34244750,
chr21:33922811-33925629~~chr21:34242516-34244705,
chr21:33922829-33925686~~chr21:34242574-34244710,
chr21:33922904-33925886~~chr21:34242518-34244755,
chr21:33923095-33925670~~chr21:34242647-34244858,
chr21:33923120-33925433~~chr21:34242660-34244787,
chr21:33923122-33925635~~chr21:34242849-34244739,
chr21:33923122-33925657~~chr21:34242859-34244409,
chr21:33923122-33925676~~chr21:34243033-34244588,
chr21:33923143-33925876~~chr21:34242626-34244598,
chr21:33923144-33925455~~chr21:34243074-34244709,
chr21:33923160-33925641~~chr21:34242525-34244685,
chr21:33923163-33925652~~chr21:34242624-34244691,
chr21:33923167-33925446~~chr21:34243125-34244618,
chr21:33923181-33925620~~chr21:34242939-34244436,
chr21:33923185-33925313~~chr21:34242635-34244717,
chr21:33923186-33925791~~chr21:34242603-34244424,
chr21:33923188-33925377~~chr21:34243095-34244510,
chr21:33923188-33925626~~chr21:34242831-34244481,
chr21:33923203-33925479~~chr21:34242612-34244684,
chr21:33923267-33925674~~chr21:34243002-34244459,
chr21:33923273-33925677~~chr21:34242680-34244482,
chr21:33923297-33925666~~chr21:34243033-34244434,
chr21:33923351-33925672~~chr21:34243120-34244473,
chr21:33923355-33925607~~chr21:34243041-34244462,
chr21:33923428-33925646~~chr21:34243111-34244377,
chr21:33925000-33950000~~chr21:34225000-34250000,
chr21:34125000-34150000~~chr21:34225000-34250000,
chr21:34133133-34135105~~chr21:34242552-34244759,
chr21:34225000-34250000~~chr21:34325000-34350000,
chr21:34225000-34250000~~chr21:34500000-34525000,
chr21:7750000-7775000~~chr21:34225000-34250000,