- Basic information
- CohesinDB ID: CDBP00417685
- Locus: chr21-34273641-34274038
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Data sourse: GSE126634, ENCSR153HNT
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Cell type: K-562, HAP1
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 0% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.978
- Subunit: SA1,Rad21
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CTCF binding site: non-CTCF
CTCF motif: False
- Genomic location: Intragenic
- 3D genome
- TAD boundary: non-Boundary
- Chromatin hubs: Hub
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Hi-C loops: True
Hi-ChIP loops: True
ChIA-PET loops: True
- Compartment:
65% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): False
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Chromatin annotation:
"15_Quies": 57%,
"14_ReprPCWk": 26%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: FOXO1, FOSL1, MEIS2, NME2, XBP1, FOXA1, PBX2, NFIC, RUNX3, PAX5, MITF, JMJD1C, MAF, TEAD1, TRIM28, BCLAF1, ETV1, NFE2L2, ESR1, OCA2, USF2, CTCF, JUN, TCF12, GATA6, IRF4, RAD51, ZNF175, EHMT2, TFAP2C, EED, POU2F2, CHD8, ZSCAN5D, TOP2A, ZBTB48, STAT1, ERG, OGG1, NFKB2, ETS1, MYC, SMARCA4, RAD21, GRHL3, RXRA, NKX2-1, BATF3, GABPA, STAT3, XRCC5, IKZF1, NFE2, NR3C1, ESRRA, CREB1, EZH2, SPI1, HCFC1R1, NCOA2, RUNX1, MAFG, CEBPA, EZH2phosphoT487, ZFX, SMAD3, CBX8, ZBTB2, RUNX2, ATF2, ETV6, PBX3, FOS, CDK8, MED1, SPDEF, MYB, C11orf30, USF1, BCL11A, TFAP2A, SP1, HNF4A, ATF7, POU2F3, PPARG, FOXA2, EBF1, CREM, GTF2B, FOXF1, ZNF662, TCF7, YY1, RELA, TARDBP, JUNB, AHR, ZFP36, BATF, TAL1, MAX, NRIP1, CBX2, NR2F2, NEUROG2, PKNOX1, NFKB1, TBX21, BHLHE40, AR, EGLN2, ZBTB42, RNF2, IKZF2, BRD4, JUND, ZNF316, FOSL2
- Target gene symbol (double-evidenced CRMs): MRPS6,RCAN1,ATP5PO,SLC5A3,ITSN1,AP000311.1
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 0
- Number of somatic mutations (non-coding): 0
- Related genes and loops
- Related gene:
ENSG00000249209,
ENSG00000205726,
ENSG00000241837,
ENSG00000243927,
ENSG00000198743,
ENSG00000159200,
- Related loop:
chr21:33675000-33700000~~chr21:34250000-34275000,
chr21:33700000-33725000~~chr21:34250000-34275000,
chr21:33775000-33800000~~chr21:34250000-34275000,
chr21:33900000-33925000~~chr21:34250000-34275000,
chr21:34050000-34075000~~chr21:34250000-34275000,
chr21:34125000-34150000~~chr21:34250000-34275000,
chr21:34150000-34175000~~chr21:34250000-34275000,
chr21:34250000-34275000~~chr21:34500000-34525000,