- Basic information
- CohesinDB ID: CDBP00417693
- Locus: chr21-34305864-34307506
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Data sourse: GSE67783, GSE86191, GSE115250, GSE206145-NatGen2015, GSE135093, ENCSR153HNT
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Cell type: Fibroblast, HCT-116, IMR-90, K-562, TC-32, HSPC
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 2% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.933
- Subunit: SA1,Rad21,SMC1,SA2,Mau2,SMC3
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CTCF binding site: CTCF
CTCF motif: False
- Genomic location: Intragenic
- 3D genome
- TAD boundary: Boundary
- Chromatin hubs: Hub
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Hi-C loops: True
Hi-ChIP loops: False
ChIA-PET loops: True
- Compartment:
65% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): False
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Chromatin annotation:
"15_Quies": 58%,
"14_ReprPCWk": 20%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: POU2F2, CHD8, SMARCA2, CEBPA, EBF1, RBPJ, ZNF534, ZFX, XBP1, MAFF, WT1, SMAD3, FOXF1, FOXA1, ZSCAN5A, SMARCC1, ERG, RELA, ATF3, RUNX2, CHD7, SOX11, CBFB, GATA3, NKX2-1, STAT3, PBX3, HAND2, MED1, ARNTL, VDR, NR3C1, KLF4, NCOA3, KMT2A, SNAI2, ESR1, OCA2, PKNOX1, C11orf30, GRHL2, ZNF334, TBX5, NCOA1, TP53, TP73, CTCF, TCF12, MAFK, SND1, ELF3, JUN, EHF, PAX3-FOXO1, NKX2-5, GATA2, ZNF479, FLI1, NOTCH3, MAZ, MRTFB, SMC3, STAG1, ZNF316
- Target gene symbol (double-evidenced CRMs): RCAN1
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 0
- Number of somatic mutations (non-coding): 0
- Related genes and loops