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Basic information

CohesinDB ID: CDBP00417698

Locus: chr21-34330025-34330426

Data sourse: ENCSR000BLD, GSE143937, GSE72082, ENCSR000BKV, GSE86191, ENCSR000EGW, ENCSR000BLY, ENCSR000BLS, GSE105028, ENCSR000ECE, GSE121355, GSE131606

Cell type: H1-hESC, HCT-116, Hep-G2, DKO, SK-N-SH, K-562, H9-hESC

DNA Sequence of binding site: UCSC hg38

Cohesin category

Peak occupancy ratio: 3% samples have this site.

Cell specificity (0: conserved, 1: cell type specific): 0.922

Subunit: SMC3,Rad21

CTCF binding site: CTCF CTCF motif: True

Genomic location: TES,Intragenic

3D genome

TAD boundary: Boundary

Chromatin hubs: Hub

Hi-C loops: True Hi-ChIP loops: True ChIA-PET loops: True

Compartment: 65% Hi-C samples shows Compartment A

Cis-regulatory elements

Enhancer (Fantom5): non-Enhancer

Super enhancer (SEdb): False

Chromatin annotation: "15_Quies": 61%, "14_ReprPCWk": 18%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).

Co-bound Transcriptional factors: CHD8, SMC1A, CBX3, MYCN, TOP2A, ZFX, ZBTB48, WT1, ZNF205, SRF, ZNF28, TBP, YY1, RELA, ZBTB2, NEUROD1, HOMEZ, RAD21, SP140, GRHL3, PRDM9, GABPA, MAX, ZNF143, MITF, TERF1, EZH2, ZNF3, STAG1, OCA2, ZNF79, L3MBTL2, ZNF334, GABPB1, CTCF, ZHX2, BRD2, BHLHE40, AR, HCFC1, RNF2, ZNF528, ZNF350, SMC3, EHMT2

Target gene symbol (double-evidenced CRMs): RCAN1,MRPS6,ITSN1,CRYZL1,URB1,AP000311.1,CBR1,SLC5A3,ATP5PO,SETD4

Function elements

Human SNPs: .

Number of somatic mutations (coding): 0

Number of somatic mutations (non-coding): 0

Related genes and loops

Related gene: ENSG00000142207, ENSG00000249209, ENSG00000205758, ENSG00000205726, ENSG00000241837, ENSG00000243927, ENSG00000198743, ENSG00000159200, ENSG00000185917, ENSG00000159228,

eachgene

Deatailed information for cohesin site CDBP00417698