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Basic information

CohesinDB ID: CDBP00417701

Locus: chr21-34339763-34340385

Data sourse: ShirahigeLab, ShirahigeLab-NatGen2015, ENCSR153HNT, GSE86191

Cell type: K-562, Fibroblast, HCT-116, RPE

DNA Sequence of binding site: UCSC hg38

Cohesin category

Peak occupancy ratio: 1% samples have this site.

Cell specificity (0: conserved, 1: cell type specific): 0.956

Subunit: SA1,Rad21,SA2

CTCF binding site: CTCF CTCF motif: False

Genomic location: Intragenic

3D genome

TAD boundary: Boundary

Chromatin hubs: Hub

Hi-C loops: True Hi-ChIP loops: True ChIA-PET loops: True

Compartment: 65% Hi-C samples shows Compartment A

Cis-regulatory elements

Enhancer (Fantom5): non-Enhancer

Super enhancer (SEdb): False

Chromatin annotation: "15_Quies": 47%, "14_ReprPCWk": 23%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).

Co-bound Transcriptional factors: FOXO1, FOSL1, MEIS2, XBP1, FOXA1, PBX2, ATF3, SMARCE1, TP63, ZNF736, NFE2L2, LMO2, ESR1, MLL, USF2, JUN, CTCF, TCF12, GATA6, PAX8, DPF2, TRIM24, SOX6, TEAD4, GATAD2A, EHMT2, GLIS1, BRD1, ZSCAN5D, MYCN, POU5F1, ZNF263, TOP2A, RUNX1T1, CTBP1, ZBTB48, ZSCAN5A, MLLT3, ERG, ETS1, MYC, SMARCA4, ARID1B, RXRA, STAT3, XRCC5, UBN1, APC, RCOR1, NFE2, DACH1, NR3C1, CEBPB, EZH2, GRHL2, ZNF565, SPI1, GATA2, RUNX1, BCL6, SOX13, ZFX, CBX8, ERG3, SMARCC1, MEF2A, ZNF384, RUNX2, GATA4, PRDM9, SMAD4, CBFA2T3, FOS, MED1, TEAD3, L3MBTL2, TBX5, USF1, MAFK, SP1, BCL11A, NR4A1, REST, TCF3, STAG1, PAX7, CBFA2T2, PPARG, FOXA2, ZNF316, CBX3, CREM, WT1, FOXF1, MEF2C, YY1, RELA, JUNB, NEUROD1, SP140, ZFP36, HIF1A, TAL1, MAX, ZNF143, GATA1, CBX2, ZFP69B, NR2F2, KAT8, TBX21, BHLHE40, AR, PAX3-FOXO1, EGR1, HSF1, RNF2, NOTCH3, BRD4, JUND, MAZ, MEF2D, AHR

Target gene symbol (double-evidenced CRMs): CRYZL1,ITSN1,ATP5PO,RCAN1,SLC5A3,URB1,CBR1,AP000311.1,MRPS6,SETD4

Function elements

Human SNPs: .

Number of somatic mutations (coding): 0

Number of somatic mutations (non-coding): 0

Related genes and loops

Related gene: ENSG00000142207, ENSG00000249209, ENSG00000205758, ENSG00000205726, ENSG00000241837, ENSG00000243927, ENSG00000198743, ENSG00000159200, ENSG00000185917, ENSG00000159228,

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Deatailed information for cohesin site CDBP00417701