- Basic information
- CohesinDB ID: CDBP00417706
- Locus: chr21-34356201-34356732
-
Data sourse: GSE206145, GSE67783, GSE86191
-
Cell type: RPE, HCT-116, HSPC
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 1% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.967
- Subunit: SA1,Rad21
-
CTCF binding site: CTCF
CTCF motif: False
- Genomic location: TES
- 3D genome
- TAD boundary: Boundary
- Chromatin hubs: Hub
-
Hi-C loops: True
Hi-ChIP loops: True
ChIA-PET loops: True
- Compartment:
65% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): True
-
Chromatin annotation:
"15_Quies": 56%,
"14_ReprPCWk": 36%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
-
Co-bound Transcriptional factors: CHD8, ZSCAN5D, ZNF366, ZNF512, HSF1, BRD4, CBX8, STAG1
- Target gene symbol (double-evidenced CRMs): RUNX1,DONSON,CFAP298-TCP10L,RCAN1,CBR1,IFNAR2,MORC3,SON,AP000295.1,SETD4,IFNGR2,AP000311.1,SLC5A3,IL10RB,DOP1B,ITSN1,ATP5PO,CRYZL1,CBR3,MRPS6
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 0
- Number of somatic mutations (non-coding): 0
- Related genes and loops
- Related gene:
ENSG00000265590,
ENSG00000249624,
ENSG00000159110,
ENSG00000243646,
ENSG00000159128,
ENSG00000159140,
ENSG00000159147,
ENSG00000249209,
ENSG00000205758,
ENSG00000205726,
ENSG00000241837,
ENSG00000243927,
ENSG00000198743,
ENSG00000159200,
ENSG00000159216,
ENSG00000185917,
ENSG00000159228,
ENSG00000159231,
ENSG00000142197,
ENSG00000159256,
- Related loop:
chr21:27500000-27525000~~chr21:34350000-34375000,
chr21:32550000-32575000~~chr21:34350000-34375000,
chr21:32825000-32850000~~chr21:34350000-34375000,
chr21:33200000-33225000~~chr21:34350000-34375000,
chr21:33275000-33300000~~chr21:34350000-34375000,
chr21:33375000-33400000~~chr21:34350000-34375000,
chr21:33575000-33600000~~chr21:34350000-34375000,
chr21:33625000-33650000~~chr21:34350000-34375000,
chr21:33650000-33675000~~chr21:34350000-34375000,
chr21:33675000-33700000~~chr21:34350000-34375000,
chr21:33900000-33925000~~chr21:34350000-34375000,
chr21:33914796-33916595~~chr21:34351238-34352674,
chr21:33922474-33925874~~chr21:34350903-34352912,
chr21:33922474-33925874~~chr21:34361152-34363316,
chr21:33922478-33925703~~chr21:34350953-34352703,
chr21:33922482-33925641~~chr21:34351260-34352734,
chr21:33922485-33925689~~chr21:34350945-34352862,
chr21:33922491-33925917~~chr21:34350938-34352700,
chr21:33922497-33925632~~chr21:34350970-34352701,
chr21:33922506-33925702~~chr21:34351099-34352751,
chr21:33922506-33925702~~chr21:34361196-34363023,
chr21:33922548-33925984~~chr21:34351060-34352696,
chr21:33922677-33925654~~chr21:34351004-34352678,
chr21:33922678-33925692~~chr21:34350968-34352861,
chr21:33922678-33925692~~chr21:34360488-34363116,
chr21:33922723-33925649~~chr21:34351297-34352672,
chr21:33922723-33925649~~chr21:34361210-34363114,
chr21:33922731-33925983~~chr21:34350999-34352701,
chr21:33922747-33925710~~chr21:34350953-34352933,
chr21:33922769-33925566~~chr21:34351244-34352677,
chr21:33922774-33925646~~chr21:34350864-34352907,
chr21:33922774-33925646~~chr21:34360816-34363118,
chr21:33922793-33925695~~chr21:34350960-34352688,
chr21:33922794-33925655~~chr21:34351015-34352657,
chr21:33922795-33925611~~chr21:34351279-34352654,
chr21:33922795-33925867~~chr21:34350963-34352941,
chr21:33922799-33925652~~chr21:34350835-34352930,
chr21:33922803-33925652~~chr21:34351268-34352724,
chr21:33922807-33925639~~chr21:34351249-34352739,
chr21:33922807-33925639~~chr21:34360481-34363035,
chr21:33922811-33925629~~chr21:34350998-34352677,
chr21:33922829-33925686~~chr21:34351316-34352521,
chr21:33922904-33925886~~chr21:34350957-34352717,
chr21:33923095-33925670~~chr21:34351032-34352705,
chr21:33923111-33925648~~chr21:34351277-34352706,
chr21:33923118-33925272~~chr21:34351281-34352636,
chr21:33923120-33925433~~chr21:34351250-34352682,
chr21:33923122-33925635~~chr21:34351299-34352659,
chr21:33923122-33925657~~chr21:34351282-34352634,
chr21:33923122-33925676~~chr21:34351224-34352662,
chr21:33923144-33925455~~chr21:34351317-34352666,
chr21:33923159-33925198~~chr21:34350968-34352744,
chr21:33923160-33925641~~chr21:34350950-34352712,
chr21:33923163-33925652~~chr21:34351238-34352674,
chr21:33923165-33925484~~chr21:34351203-34352904,
chr21:33923167-33925446~~chr21:34351265-34352679,
chr21:33923182-33925354~~chr21:34350993-34352702,
chr21:33923185-33925313~~chr21:34351263-34352734,
chr21:33923186-33925791~~chr21:34351258-34352706,
chr21:33923188-33925377~~chr21:34351052-34352697,
chr21:33923188-33925626~~chr21:34351053-34352749,
chr21:33923188-33925626~~chr21:34361201-34363001,
chr21:33923203-33925479~~chr21:34351078-34352698,
chr21:33923225-33925528~~chr21:34351176-34352652,
chr21:33923267-33925674~~chr21:34351237-34352679,
chr21:33923268-33925281~~chr21:34351254-34352712,
chr21:33923273-33925677~~chr21:34351214-34352694,
chr21:33923297-33925666~~chr21:34351254-34352629,
chr21:33923337-33925670~~chr21:34351266-34352642,
chr21:33923351-33925672~~chr21:34351295-34352620,
chr21:33923354-33925674~~chr21:34351230-34352630,
chr21:33923355-33925607~~chr21:34351298-34352601,
chr21:33923364-33925673~~chr21:34351290-34352549,
chr21:33925000-33950000~~chr21:34350000-34375000,
chr21:33950000-33975000~~chr21:34350000-34375000,
chr21:34050000-34075000~~chr21:34350000-34375000,
chr21:34072055-34075610~~chr21:34350835-34352930,
chr21:34072203-34075604~~chr21:34350950-34352712,
chr21:34072301-34075531~~chr21:34350864-34352907,
chr21:34100000-34125000~~chr21:34350000-34375000,
chr21:34128593-34130330~~chr21:34351015-34352657,
chr21:34350000-34375000~~chr21:34500000-34525000,
chr21:34350000-34375000~~chr21:34525000-34550000,
chr21:34350000-34375000~~chr21:34550000-34575000,
chr21:34350000-34375000~~chr21:34575000-34600000,
chr21:34350000-34375000~~chr21:34600000-34625000,
chr21:34350000-34375000~~chr21:34625000-34650000,
chr21:34350000-34375000~~chr21:34725000-34750000,
chr21:34350000-34375000~~chr21:34750000-34775000,
chr21:34350000-34375000~~chr21:34775000-34800000,
chr21:34350000-34375000~~chr21:34800000-34825000,
chr21:34350000-34375000~~chr21:34825000-34850000,
chr21:34350000-34375000~~chr21:34850000-34875000,
chr21:34350000-34375000~~chr21:34875000-34900000,
chr21:34350000-34375000~~chr21:34950000-34975000,
chr21:34350000-34375000~~chr21:34975000-35000000,
chr21:34350000-34375000~~chr21:35000000-35025000,
chr21:34350000-34375000~~chr21:35025000-35050000,
chr21:34350000-34375000~~chr21:35100000-35125000,
chr21:34350000-34375000~~chr21:35125000-35150000,
chr21:34350000-34375000~~chr21:35150000-35175000,
chr21:34350000-34375000~~chr21:35175000-35200000,
chr21:34350000-34375000~~chr21:35200000-35225000,
chr21:34350000-34375000~~chr21:35225000-35250000,
chr21:34350000-34375000~~chr21:35250000-35275000,
chr21:34350000-34375000~~chr21:35275000-35300000,
chr21:34350000-34375000~~chr21:35300000-35325000,
chr21:34350000-34375000~~chr21:35325000-35350000,
chr21:34350000-34375000~~chr21:35350000-35375000,
chr21:34350000-34375000~~chr21:35400000-35425000,
chr21:34350000-34375000~~chr21:35425000-35450000,
chr21:34350000-34375000~~chr21:35500000-35525000,
chr21:34350000-34375000~~chr21:35525000-35550000,
chr21:34350000-34375000~~chr21:35550000-35575000,
chr21:34350000-34375000~~chr21:35575000-35600000,
chr21:34350000-34375000~~chr21:35600000-35625000,
chr21:34350000-34375000~~chr21:35625000-35650000,
chr21:34350000-34375000~~chr21:35650000-35675000,
chr21:34350000-34375000~~chr21:35675000-35700000,
chr21:34350000-34375000~~chr21:35700000-35725000,
chr21:34350000-34375000~~chr21:35725000-35750000,
chr21:34350000-34375000~~chr21:35800000-35825000,
chr21:34350000-34375000~~chr21:35825000-35850000,
chr21:34350000-34375000~~chr21:35850000-35875000,
chr21:34350000-34375000~~chr21:35900000-35925000,
chr21:34350000-34375000~~chr21:35925000-35950000,
chr21:34350000-34375000~~chr21:35950000-35975000,
chr21:34350000-34375000~~chr21:36000000-36025000,
chr21:34350000-34375000~~chr21:36025000-36050000,
chr21:34350000-34375000~~chr21:36050000-36075000,
chr21:34350000-34375000~~chr21:36075000-36100000,
chr21:34350000-34375000~~chr21:36100000-36125000,
chr21:34350000-34375000~~chr21:36125000-36150000,
chr21:34350000-34375000~~chr21:36225000-36250000,
chr21:34350000-34375000~~chr21:36275000-36300000,
chr21:34350000-34375000~~chr21:36300000-36325000,
chr21:34350000-34375000~~chr21:36325000-36350000,
chr21:34350000-34375000~~chr21:36375000-36400000,
chr21:34350000-34375000~~chr21:36400000-36425000,
chr21:34350000-34375000~~chr21:36500000-36525000,
chr21:34350000-34375000~~chr21:36550000-36575000,
chr21:34350000-34375000~~chr21:36900000-36925000,
chr21:34350000-34375000~~chr21:37050000-37075000,
chr21:34350000-34375000~~chr21:37200000-37225000,
chr21:34350000-34375000~~chr21:37250000-37275000,
chr21:34350000-34375000~~chr21:37275000-37300000,
chr21:34350000-34375000~~chr21:37600000-37625000,
chr21:34350000-34375000~~chr21:39175000-39200000,
chr21:34350000-34375000~~chr21:39375000-39400000,
chr21:34350000-34375000~~chr21:42975000-43000000,
chr21:34360428-34363003~~chr21:34602198-34604029,
chr21:34360466-34363118~~chr21:34629724-34631850,
chr21:34360469-34363186~~chr21:34629535-34631912,
chr21:34360481-34363035~~chr21:34629707-34631944,
chr21:34360488-34363116~~chr21:34602101-34604451,
chr21:34360488-34363116~~chr21:34634839-34636188,
chr21:34360738-34363146~~chr21:34629695-34631822,
chr21:34360816-34363118~~chr21:34629714-34631894,
chr21:34361194-34362922~~chr21:34629718-34631638,
chr21:34361195-34362791~~chr21:34629715-34631594,
chr21:34361196-34363023~~chr21:34629772-34631610,
chr21:34361198-34363034~~chr21:34629528-34631714,
chr21:34361206-34363004~~chr21:34629693-34631699,
chr21:34361208-34362935~~chr21:34629754-34631604,
chr21:34361209-34363099~~chr21:34629560-34631658,
chr21:34361210-34363114~~chr21:34629958-34631796,
chr21:34361281-34362787~~chr21:34629952-34631423,
chr21:7750000-7775000~~chr21:34350000-34375000,
chr21:7800000-7825000~~chr21:34350000-34375000,