- Basic information
- CohesinDB ID: CDBP00417712
- Locus: chr21-34371955-34372730
-
Data sourse: ENCSR167MTG, GSE67783, GSE72082, GSE86191, GSE111913, ENCSR000BLS, ENCSR054FKH, ENCSR153HNT, ENCSR000EDW
-
Cell type: HCT-116, Hep-G2, RT-112, K-562, HSPC
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 2% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.944
- Subunit: SMC3,Rad21,SA2,SA1
-
CTCF binding site: non-CTCF
CTCF motif: False
- Genomic location: TSS,TES
- 3D genome
- TAD boundary: Boundary
- Chromatin hubs: Hub
-
Hi-C loops: True
Hi-ChIP loops: True
ChIA-PET loops: True
- Compartment:
65% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): True
-
Chromatin annotation:
"15_Quies": 52%,
"14_ReprPCWk": 23%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
-
Co-bound Transcriptional factors: NFIA, PGR, HMG20A, XBP1, FOXA1, RXRB, PBX2, KDM3A, TFAP4, TSC22D4, ATF3, THRB, THAP1, PRDM1, ATF4, MXD4, TEAD1, ELF1, ZNF573, KLF6, TRIM28, KLF10, RCOR2, ESR1, OCA2, LMO2, MLL, USF2, CTCF, TCF12, EP300, SOX5, DMAP1, SOX6, ZNF528, FOXA3, ZNF175, GATAD2A, RBPJ, MLX, EED, TFAP2C, POU2F2, CHD8, MYCN, HHEX, TOP2A, POU5F1, ZBTB17, ZBTB48, GATAD1, SAP130, ARID3A, HNF4G, ERG, OGG1, ETS1, MYC, SMARCA4, HOMEZ, RAD21, GRHL3, RXRA, ZNF614, XRCC5, MIER3, NFE2, NR2F6, CEBPB, ESRRA, KMT2A, CREB1, TBL1XR1, EZH2, ZNF652, GABPB1, SPI1, MIXL1, TFE3, HDAC2, GATA2, ZNF644, FLI1, DRAP1, ZGPAT, NFIL3, ETV5, THAP11, BCL6, CEBPA, SOX13, ZFX, POU4F2, SMAD3, SP5, RARA, ZNF384, ARNT, ATF2, ZNF48, SMAD4, FOS, HMGXB4, SMARCB1, TEAD3, CEBPD, ZNF22, SP1, HNF4A, IKZF5, ATF7, ASH2L, PHIP, FOXP1, SMC3, ZNF394, SKI, PPARG, FOXA2, CREM, TCF7, ZNF580, HOXB13, KDM1A, YY1, RELA, MCM3, ZFP36, HIF1A, GATA3, MAX, ZNF143, GATA1, CEBPG, NCOA3, NR2F2, TP53, PKNOX1, ZSCAN22, ELF3, PHF5A, KAT8, BRD2, ARID4B, NFKBIZ, BHLHE40, AR, ZBTB26, NCOR1, NOTCH3, JUND, BRD4, CUX1, SMAD4.1D12, AHR
- Target gene symbol (double-evidenced CRMs): DOP1B,CRYZL1,RUNX1,SETD4,SMIM11A,IFNAR2,IL10RB,MRPS6,IFNGR2,ATP5PO,AP000295.1,CFAP298-TCP10L,RCAN1,ITSN1,CBR3,SLC5A3,MORC3,DONSON,CBR1,AP000311.1,SON
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 0
- Number of somatic mutations (non-coding): 0
- Related genes and loops
- Related gene:
ENSG00000265590,
ENSG00000249624,
ENSG00000159110,
ENSG00000243646,
ENSG00000159128,
ENSG00000159140,
ENSG00000159147,
ENSG00000249209,
ENSG00000205758,
ENSG00000205726,
ENSG00000241837,
ENSG00000243927,
ENSG00000198743,
ENSG00000205670,
ENSG00000159200,
ENSG00000159216,
ENSG00000185917,
ENSG00000159228,
ENSG00000159231,
ENSG00000142197,
ENSG00000159256,
- Related loop:
chr21:27500000-27525000~~chr21:34350000-34375000,
chr21:32550000-32575000~~chr21:34350000-34375000,
chr21:32825000-32850000~~chr21:34350000-34375000,
chr21:33200000-33225000~~chr21:34350000-34375000,
chr21:33275000-33300000~~chr21:34350000-34375000,
chr21:33375000-33400000~~chr21:34350000-34375000,
chr21:33575000-33600000~~chr21:34350000-34375000,
chr21:33625000-33650000~~chr21:34350000-34375000,
chr21:33650000-33675000~~chr21:34350000-34375000,
chr21:33675000-33700000~~chr21:34350000-34375000,
chr21:33900000-33925000~~chr21:34350000-34375000,
chr21:33925000-33950000~~chr21:34350000-34375000,
chr21:33950000-33975000~~chr21:34350000-34375000,
chr21:34050000-34075000~~chr21:34350000-34375000,
chr21:34100000-34125000~~chr21:34350000-34375000,
chr21:34350000-34375000~~chr21:34500000-34525000,
chr21:34350000-34375000~~chr21:34525000-34550000,
chr21:34350000-34375000~~chr21:34550000-34575000,
chr21:34350000-34375000~~chr21:34575000-34600000,
chr21:34350000-34375000~~chr21:34600000-34625000,
chr21:34350000-34375000~~chr21:34625000-34650000,
chr21:34350000-34375000~~chr21:34725000-34750000,
chr21:34350000-34375000~~chr21:34750000-34775000,
chr21:34350000-34375000~~chr21:34775000-34800000,
chr21:34350000-34375000~~chr21:34800000-34825000,
chr21:34350000-34375000~~chr21:34825000-34850000,
chr21:34350000-34375000~~chr21:34850000-34875000,
chr21:34350000-34375000~~chr21:34875000-34900000,
chr21:34350000-34375000~~chr21:34950000-34975000,
chr21:34350000-34375000~~chr21:34975000-35000000,
chr21:34350000-34375000~~chr21:35000000-35025000,
chr21:34350000-34375000~~chr21:35025000-35050000,
chr21:34350000-34375000~~chr21:35100000-35125000,
chr21:34350000-34375000~~chr21:35125000-35150000,
chr21:34350000-34375000~~chr21:35150000-35175000,
chr21:34350000-34375000~~chr21:35175000-35200000,
chr21:34350000-34375000~~chr21:35200000-35225000,
chr21:34350000-34375000~~chr21:35225000-35250000,
chr21:34350000-34375000~~chr21:35250000-35275000,
chr21:34350000-34375000~~chr21:35275000-35300000,
chr21:34350000-34375000~~chr21:35300000-35325000,
chr21:34350000-34375000~~chr21:35325000-35350000,
chr21:34350000-34375000~~chr21:35350000-35375000,
chr21:34350000-34375000~~chr21:35400000-35425000,
chr21:34350000-34375000~~chr21:35425000-35450000,
chr21:34350000-34375000~~chr21:35500000-35525000,
chr21:34350000-34375000~~chr21:35525000-35550000,
chr21:34350000-34375000~~chr21:35550000-35575000,
chr21:34350000-34375000~~chr21:35575000-35600000,
chr21:34350000-34375000~~chr21:35600000-35625000,
chr21:34350000-34375000~~chr21:35625000-35650000,
chr21:34350000-34375000~~chr21:35650000-35675000,
chr21:34350000-34375000~~chr21:35675000-35700000,
chr21:34350000-34375000~~chr21:35700000-35725000,
chr21:34350000-34375000~~chr21:35725000-35750000,
chr21:34350000-34375000~~chr21:35800000-35825000,
chr21:34350000-34375000~~chr21:35825000-35850000,
chr21:34350000-34375000~~chr21:35850000-35875000,
chr21:34350000-34375000~~chr21:35900000-35925000,
chr21:34350000-34375000~~chr21:35925000-35950000,
chr21:34350000-34375000~~chr21:35950000-35975000,
chr21:34350000-34375000~~chr21:36000000-36025000,
chr21:34350000-34375000~~chr21:36025000-36050000,
chr21:34350000-34375000~~chr21:36050000-36075000,
chr21:34350000-34375000~~chr21:36075000-36100000,
chr21:34350000-34375000~~chr21:36100000-36125000,
chr21:34350000-34375000~~chr21:36125000-36150000,
chr21:34350000-34375000~~chr21:36225000-36250000,
chr21:34350000-34375000~~chr21:36275000-36300000,
chr21:34350000-34375000~~chr21:36300000-36325000,
chr21:34350000-34375000~~chr21:36325000-36350000,
chr21:34350000-34375000~~chr21:36375000-36400000,
chr21:34350000-34375000~~chr21:36400000-36425000,
chr21:34350000-34375000~~chr21:36500000-36525000,
chr21:34350000-34375000~~chr21:36550000-36575000,
chr21:34350000-34375000~~chr21:36900000-36925000,
chr21:34350000-34375000~~chr21:37050000-37075000,
chr21:34350000-34375000~~chr21:37200000-37225000,
chr21:34350000-34375000~~chr21:37250000-37275000,
chr21:34350000-34375000~~chr21:37275000-37300000,
chr21:34350000-34375000~~chr21:37600000-37625000,
chr21:34350000-34375000~~chr21:39175000-39200000,
chr21:34350000-34375000~~chr21:39375000-39400000,
chr21:34350000-34375000~~chr21:42975000-43000000,
chr21:34366756-34368545~~chr21:34629560-34631658,
chr21:34366762-34368585~~chr21:34602009-34603991,
chr21:34366762-34368585~~chr21:34629714-34631894,
chr21:34366789-34368462~~chr21:34629724-34631850,
chr21:34366803-34368417~~chr21:34629516-34631784,
chr21:34366854-34368356~~chr21:34629657-34631644,
chr21:34366856-34368482~~chr21:34629869-34631575,
chr21:34366866-34368178~~chr21:34630024-34631895,
chr21:34366877-34368476~~chr21:34629552-34632018,
chr21:34366893-34368392~~chr21:34629528-34631714,
chr21:34366895-34368186~~chr21:34630001-34631676,
chr21:34366900-34368462~~chr21:34629794-34631884,
chr21:7750000-7775000~~chr21:34350000-34375000,
chr21:7800000-7825000~~chr21:34350000-34375000,