Browse_each

Basic information

CohesinDB ID: CDBP00417749

Locus: chr21-34533706-34535019

Data sourse: GSE206145-GSE177045, GSE67783, GSE86191, GSE98367, GSE116868, GSE111913, GSE206145, GSE206145-NatGen2015, ENCSR000BMY, ENCSR153HNT, GSE68388, GSE111537, GSE165895

Cell type: MCF-7, Macrophage, RPE, Fibroblast, HCT-116, MB157, GM12878, RT-112, K-562, OCI-AML-3, HSPC, HuCC-T1, HFFc6

DNA Sequence of binding site: UCSC hg38

Cohesin category

Peak occupancy ratio: 4% samples have this site.

Cell specificity (0: conserved, 1: cell type specific): 0.856

Subunit: SA1,Rad21,SMC1,SA2,Mau2

CTCF binding site: CTCF CTCF motif: False

Genomic location: Intragenic

3D genome

TAD boundary: non-Boundary

Chromatin hubs: Hub

Hi-C loops: True Hi-ChIP loops: True ChIA-PET loops: True

Compartment: 93% Hi-C samples shows Compartment A

Cis-regulatory elements

Enhancer (Fantom5): non-Enhancer

Super enhancer (SEdb): True

Chromatin annotation: "15_Quies": 37%, "5_TxWk": 31%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).

Co-bound Transcriptional factors: FOXO1, FOSL1, PGR, SOX2, NME2, XBP1, FOXA1, HDGF, ZNF90, ATF3, RUNX3, CHD7, PRDM1, CBFB, ZNF189, MECOM, PAX5, TP63, MITF, JMJD1C, MAF, ELF1, TRIM28, BCLAF1, TEAD1, LMO2, ESR1, OCA2, TP73, MLL, USF2, JUN, CTCF, TCF12, EP300, SND1, KLF1, GATA6, DPF2, PAX8, IRF4, E2F1, TEAD4, KMT2B, RBPJ, EED, TFAP2C, GLIS1, POU2F2, CHD8, MYCN, SRC, TOP2A, ID3, RUNX1T1, POU5F1, MTA2, CDK7, ZBTB48, ZSCAN5A, KDM4C, DUX4, MLLT3, SAP130, NBN, ERG, ETS1, EZH1, MYC, SMARCA4, RAD21, GRHL3, RXRA, BATF3, STAT3, XRCC5, APC, PRDM14, IKZF1, NFE2, HNRNPH1, VDR, NR3C1, CEBPB, ESRRA, STAT5B, KMT2A, EZH2, GRHL2, ZHX2, SPI1, GATA2, ZNF644, GATAD2B, MXD3, FLI1, RELB, MRTFB, NCOA2, RUNX1, SMC1A, CEBPA, LDB1, CRY1, SIN3A, ZFX, SOX13, ZNF534, SMAD3, TET2, SMARCC1, ZBTB2, CREBBP, ZNF384, RUNX2, GATA4, ARNT, DAXX, PBX4, PRDM9, FOXM1, PBX3, CDK8, MED1, ZEB1, TEAD3, MYB, ZMYM3, SUPT16H, ZNF3, TBX5, STAT5A, RBM22, SP1, BCL11A, NR4A1, HNF4A, ATF7, POU2F3, ZNF263, TCF3, SMC3, MLLT1, STAG1, NFATC3, PAX7, MEF2B, PPARG, TBL1X, ZNF316, EBF1, SS18, ZNF600, WT1, ESR2, MEF2C, CDK9, HOXB13, KDM1A, YY1, RELA, TARDBP, JUNB, SP140, ZIC2, HIF1A, SKIL, OTX2, GATA3, BATF, MAX, NRIP1, GATA1, TLE3, KLF4, NCOA3, NR2F2, NR2F1, KDM5B, TP53, ZNF687, MED, ZNF334, BRD2, ELF3, TBX21, BHLHE40, AR, YAP1, RXR, RB1, HSF1, NOTCH3, BRD4, IKZF2, JUND, MAZ, AHR, FOSL2

Target gene symbol (double-evidenced CRMs): AP000311.1,RCAN1,SMIM11A,ATP5PO,RUNX1,ITSN1

Function elements

Human SNPs: .

Number of somatic mutations (coding): 12

Number of somatic mutations (non-coding): 0

Related genes and loops

Related gene: ENSG00000249209, ENSG00000205726, ENSG00000241837, ENSG00000205670, ENSG00000159200, ENSG00000159216,

eachgene

Deatailed information for cohesin site CDBP00417749