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Basic information

CohesinDB ID: CDBP00417755

Locus: chr21-34547080-34547346

Data sourse: GSE67783, ENCSR153HNT

Cell type: K-562, HSPC

DNA Sequence of binding site: UCSC hg38

Cohesin category

Peak occupancy ratio: 1% samples have this site.

Cell specificity (0: conserved, 1: cell type specific): 0.978

Subunit: SA1

CTCF binding site: non-CTCF CTCF motif: False

Genomic location: Intragenic

3D genome

TAD boundary: non-Boundary

Chromatin hubs: Hub

Hi-C loops: True Hi-ChIP loops: True ChIA-PET loops: True

Compartment: 93% Hi-C samples shows Compartment A

Cis-regulatory elements

Enhancer (Fantom5): non-Enhancer

Super enhancer (SEdb): True

Chromatin annotation: "15_Quies": 42%, "7_Enh": 28%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).

Co-bound Transcriptional factors: FOXO1, NFIA, ZNF195, FOXA1, HLF, RXRB, MLL4, KDM3A, HDGF, ZBTB44, PAX5, TEAD1, E2F5, LMO2, OCA2, HDAC8, ZNF561, ZNF577, E4F1, SOX5, DEK, NR5A2, ZNF528, KMT2B, GATAD2A, NANOG, POU5F1, BRD3, CTBP1, STAT1, ZNF563, SAP130, ERG, ZNF597, SMARCA4, RCOR1, NR2F6, CD74, CEBPB, CREB1, GABPB1, ZHX2, MIXL1, GATA2, ZNF644, MXD3, FLI1, DRAP1, MXI1, NR2C2, HCFC1, RELB, RUNX1, CEBPA, HDAC1, ZNF473, ZNF654, TBX3, SP5, TRIM22, ZNF549, PRDM10, SMARCC1, ZBTB2, SOX11, ATF2, FOXM1, ZNF584, TERF1, PML, PIAS1, SMAD1, NR1H2, C11orf30, EVI1, MBD1, ARID2, IKZF5, RBM25, AFF1, ELL2, NFATC3, CBFA2T2, MEF2B, ZNF207, CBX3, CREM, CHD2, SS18, PAF1, NFATC1, WT1, MEF2C, NEUROD1, JUNB, ZNF510, ZFP36, TCF4, BATF, SPIB, ZSCAN26, KLF4, ZKSCAN8, ZNF544, MED, BCL6B, ELF3, ARID4B, RXR, EGLN2, ZBTB26, NCOR1, ZNF316, FOSL1, ZNF660, XBP1, PBX2, ATF3, ZFP64, RUNX3, CBFB, MITF, JMJD1C, MAF, INTS11, ELF1, RBM39, KLF10, ZNF624, ZIK1, CTCF, JUN, DPF2, IRF4, DDX20, ZNF776, ZNF350, RBPJ, TFAP2C, ZNF317, MTA2, SRF, NBN, ZNF626, HOMEZ, RXRA, BATF3, PRDM14, MIER3, TERF2, LEF1, VDR, NR3C1, ESRRA, KMT2A, CCAR2, TBL1XR1, KLF8, GRHL2, EBF3, SSRP1, SMARCA5, NFIL3, THAP11, SOX13, AFF4, ZNF770, ZNF18, NFIB, ARNT, BACH1, DAXX, ZNF48, ZEB2, NFYA, HMBOX1, PBX3, ETV6, HMGXB4, ICE2, TEAD3, U2AF1, TAF7, KLF9, TBX5, ZNF37A, BCL11A, SP1, ATF7, ASH2L, PRDM6, SMC3, STAT2, STAG2, STAG1, MLLT1, MTA3, EBF1, MEIS1, MAFF, ZNF580, ZKSCAN1, BCL3, KDM1A, ZNF830, ZIC2, GATA3, TAL1, NRIP1, ZNF143, TP53, ZNF334, NFKB1, BRD2, KAT8, TBX21, EGR1, RB1, RNF2, IKZF2, BRD4, JUND, PGR, SOX2, TFAP4, SIN3B, ZNF112, CHD7, ZNF444, ATF4, MXD4, ZNF189, SMARCE1, MZF1, KLF6, NFE2L2, ZNF217, ESR1, TP73, SND1, SOX9, SOX4, TRIM24, ZNF92, GTF2F1, POU2F2, ZSCAN5A, TBP, HNF4G, ETS1, MYC, ARID1B, STAT3, SOX10, IKZF1, DNMT3B, EZH2, SPI1, HDAC2, INTS13, GATAD2B, NCOA2, ETV5, BCL6, SIN3A, ERG3, MEF2A, RARA, ZNF384, ZNF35, CREBBP, NFYC, HMGB2, SMAD4, CBFA2T3, CDK8, ZMYM3, RBM22, MAFK, HNF4A, NR4A1, REST, ARID1A, ZHX1, BCOR, FOXP1, NCOR2, PTTG1, PPARG, TBL1X, ZNF716, ZNF44, GTF2B, ZNF174, ZNF662, TCF7, ZNF318, RELA, TARDBP, SKIL, MAX, GFI1B, NR2F1, KDM5B, PKNOX1, T, AR, ZBTB16, YAP1, ZNF324, ZNF395, DMAP1, AHR, FOSL2, HMG20A, LCORL, E2F7, RBFOX2, ZNF529, NFIC, CTCFL, KLF14, MECOM, CDX2, KLF5, TRIM28, BCLAF1, ETV1, RCOR2, MLL, USF2, TCF12, EP300, GATA6, CREB3, SOX6, E2F1, SMC1, TEAD4, FOXA3, ZNF175, ZNF491, EED, CHD8, MYCN, CDK7, ID3, RUNX1T1, MLLT3, GATAD1, ARID3A, ZNF300, RAD21, GRHL3, PROX1, APC, XRCC5, ZNF614, NFE2, ZNF667, ZNF93, TRPS1, TFE3, HBP1, EHF, IRF1, SREBF1, ZGPAT, MRTFB, ZIM3, MYF5, SMC1A, CBX1, MAFG, FIP1L1, ZFX, SMAD3, IRF2, RUNX2, CDK6, GATA4, OSR2, ZNF184, PBX4, NR2C1, FOS, MED1, CEBPD, MYB, ZNF3, L3MBTL2, SETDB1, NIPBL, ZBTB7A, POU2F3, PHIP, TCF3, SKI, ZNF283, KLF13, FOXA2, MIER2, ZBED1, CDK9, HOXB13, ZNF589, YY1, ZNF148, SP140, HIF1A, OTX2, TLE3, CEBPG, NCOA3, NR2F2, ZNF83, NFKBIZ, BHLHE40, TAF1, ZNF579, MYNN, ZNF248, MAZ, MEF2D, ZNF24

Target gene symbol (double-evidenced CRMs): SMIM11A,ITSN1,RUNX1,ATP5PO,AP000311.1,RCAN1

Function elements

Human SNPs: .

Number of somatic mutations (coding): 0

Number of somatic mutations (non-coding): 0

Related genes and loops

Related gene: ENSG00000249209, ENSG00000205726, ENSG00000241837, ENSG00000205670, ENSG00000159200, ENSG00000159216,

eachgene

Deatailed information for cohesin site CDBP00417755