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Basic information

CohesinDB ID: CDBP00417757

Locus: chr21-34551283-34551653

Data sourse: GSE206145-NatGen2015

Cell type: Fibroblast

DNA Sequence of binding site: UCSC hg38

Cohesin category

Peak occupancy ratio: 0% samples have this site.

Cell specificity (0: conserved, 1: cell type specific): 0.989

Subunit: Mau2

CTCF binding site: non-CTCF CTCF motif: False

Genomic location: Intragenic

3D genome

TAD boundary: non-Boundary

Chromatin hubs: Hub

Hi-C loops: True Hi-ChIP loops: False ChIA-PET loops: True

Compartment: 93% Hi-C samples shows Compartment A

Cis-regulatory elements

Enhancer (Fantom5): non-Enhancer

Super enhancer (SEdb): True

Chromatin annotation: "15_Quies": 59%, "5_TxWk": 33%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).

Co-bound Transcriptional factors: FOXO1, FOSL1, PGR, SMARCA2, SOX2, MEIS2, FOXA1, PBX2, ATF3, NFIC, CHD7, PRDM1, RUNX3, SMARCE1, MITF, CDX2, JMJD1C, TEAD1, ELF1, TRIM28, ETV1, NFE2L2, ESR1, MLL, OCA2, JUN, TCF12, CTCF, BAF155, EP300, IRF4, E2F1, TEAD4, PDX1, TFAP2C, EED, NANOG, CHD8, MYCN, DUX4, STAT1, SRF, ZNF485, ERG, HOXC5, ETS1, MYC, SMARCA4, RFX1, GRHL3, RXRA, GABPA, STAT3, NKX3-1, IKZF1, ARNTL, VDR, NR3C1, CEBPB, KMT2A, CREB1, GRHL2, TRPS1, ZHX2, SPI1, EHF, GATA2, FLI1, MRTFB, RUNX1, SMC1A, CEBPA, SIN3A, SMAD3, TWIST1, SMARCC1, CREBBP, RUNX2, PBX4, ARNT, DAXX, PBX3, FOXM1, FOS, CDK8, MED1, ZEB1, MYB, PIAS1, NR1H2, NCOA1, SETDB1, SP1, REST, ASH2L, TCF3, FOXP1, NCOR2, MLLT1, PPARG, FOXA2, CBX3, MEIS1, SS18, NFATC1, MEF2C, CDK9, HOXB13, YY1, RELA, JUNB, ZNF148, TCF4, HIF1A, ZIC2, GATA3, BATF, TAL1, MAX, NR2F2, NEUROG2, KDM5B, TP53, ZNF334, BRD2, ELF3, BHLHE40, AR, TAF1, RXR, EGLN2, NCOR1, BRD4, JUND, CUX1, FOSL2

Target gene symbol (double-evidenced CRMs): SMIM11A,RCAN1,RUNX1

Function elements

Human SNPs: .

Number of somatic mutations (coding): 8

Number of somatic mutations (non-coding): 0

Related genes and loops

Related gene: ENSG00000205670, ENSG00000159200, ENSG00000159216,

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Deatailed information for cohesin site CDBP00417757