- Basic information
- CohesinDB ID: CDBP00417761
- Locus: chr21-34558172-34558436
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Data sourse: GSE85526, GSE111913, ENCSR153HNT, GSE86191
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Cell type: K-562, RT-112, HCT-116, HEKn
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 1% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.956
- Subunit: SA1,Rad21,SA2,SMC1
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CTCF binding site: non-CTCF
CTCF motif: False
- Genomic location: Intragenic
- 3D genome
- TAD boundary: non-Boundary
- Chromatin hubs: Hub
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Hi-C loops: True
Hi-ChIP loops: False
ChIA-PET loops: True
- Compartment:
93% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): True
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Chromatin annotation:
"15_Quies": 70%,
"5_TxWk": 17%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: PAX7, NFIA, CBFA2T2, CHD8, SMC1A, CEBPA, PGR, EBF1, RUNX1T1, SS18, ZFX, CDK7, XBP1, POU5F1, SIRT6, DUX4, FOXA1, SRF, ERG3, CBX8, ZNF513, CDK9, ZNF28, ZFHX2, ERG2, ERG, YY1, RELA, JUNB, MYC, SMARCA4, ZKSCAN2, RUNX3, CHD7, GRHL3, NRF1, HIF1A, PRDM9, BATF, ZNF189, MAX, TP63, SOX10, ZNF143, IKZF1, MITF, RCOR1, FOS, FOXM1, PLAG1, KLF4, TEAD3, TEAD1, ETV1, TFAP2C, KDM5B, ZNF3, ESR1, EZH2, BMPR1A, GRHL2, USF2, EGR2, CTCF, BRD2, USF1, JUN, BHLHE40, AR, ZBTB16, REST, IRF4, FOSL2, FLI1, HSF1, RAD51, NOTCH3, BRD4, POU2F3, TEAD4, POU2F2, ZNF175, RBPJ, EED
- Target gene symbol (double-evidenced CRMs): RCAN1,RUNX1,SMIM11A
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 4
- Number of somatic mutations (non-coding): 0
- Related genes and loops