- Basic information
- CohesinDB ID: CDBP00417767
- Locus: chr21-34570400-34570594
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Data sourse: GSE111537, GSE98367
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Cell type: OCI-AML-3, Macrophage
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 0% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.978
- Subunit: SA2,SMC1
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CTCF binding site: non-CTCF
CTCF motif: False
- Genomic location: Intragenic
- 3D genome
- TAD boundary: non-Boundary
- Chromatin hubs: Hub
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Hi-C loops: True
Hi-ChIP loops: False
ChIA-PET loops: True
- Compartment:
93% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): True
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Chromatin annotation:
"15_Quies": 55%,
"5_TxWk": 31%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: PGR, SOX2, XBP1, FOXA1, SUZ12, LYL1, ATF3, NFIC, CHD7, RUNX3, PAX5, ZNF736, JMJD1C, TEAD1, TRIM28, LMO2, ESR1, MLL, TP73, USF2, JUN, CTCF, BAF155, KLF1, PAX8, DPF2, TRIM24, TEAD4, KMT2B, TFAP2C, EED, POU2F2, CHD8, MYCN, ZNF263, TOP2A, RUNX1T1, CTBP1, MTA2, ZBTB48, ZSCAN5A, STAT1, ZNF205, ZNF134, DDX5, ERG2, ERG, OGG1, MYC, SMARCA4, RAD21, GABPA, STAT3, NKX3-1, RCOR1, VDR, NR3C1, CEBPB, KMT2A, CREB1, EZH2, GRHL2, TRPS1, SPI1, HDAC2, GATA2, INTS13, ZNF766, NCOA2, RUNX1, BCL6, SMC1A, CEBPA, LDB1, SIN3A, ZFX, SMAD3, CREBBP, ZNF384, RUNX2, CDK6, PBX4, ARNT, ZNF10, FOS, CDK8, MED1, ZEB1, TERF1, TEAD3, ZNF558, SCRT2, PIAS1, MYB, TBX5, EVI1, STAT5A, BCL11A, SP1, HOXA9, CTBP2, FOXP1, SMC3, STAG1, MLLT1, FOXA2, MTA3, EBF1, MEIS1, WT1, ZBTB33, MEF2C, CDK9, HOXB13, RELA, JUNB, AHR, SP140, ZFP36, HIF1A, GATA3, TAL1, MAX, GATA1, ZNF143, TLE3, NCOA3, NR2F2, TCF7L2, KDM5B, TP53, ZNF334, AR, ZNF579, BRD4, SCRT1, MAZ, ZNF316
- Target gene symbol (double-evidenced CRMs): RCAN1,SMIM11A,RUNX1
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 0
- Number of somatic mutations (non-coding): 0
- Related genes and loops
- Related gene:
ENSG00000205670,
ENSG00000159200,
ENSG00000159216,
- Related loop:
chr21:33975000-34000000~~chr21:34550000-34575000,
chr21:34350000-34375000~~chr21:34550000-34575000,
chr21:34350000-34375000~~chr21:34575000-34600000,
chr21:34543283-34546348~~chr21:34575254-34577002,
chr21:34550000-34575000~~chr21:34850000-34875000,
chr21:7800000-7825000~~chr21:34550000-34575000,
chr21:7800000-7825000~~chr21:34575000-34600000,