- Basic information
- CohesinDB ID: CDBP00417768
- Locus: chr21-34571564-34572414
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Data sourse: ENCSR230ZWH, GSE67783, GSE72082, GSE138405, ENCSR000BLS, ENCSR153HNT, ENCSR917QNE
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Cell type: Hela-Kyoto, Hep-G2, K-562, Liver, HSPC
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 2% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.944
- Subunit: SA1,Rad21,SA2
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CTCF binding site: non-CTCF
CTCF motif: False
- Genomic location: Intragenic
- 3D genome
- TAD boundary: non-Boundary
- Chromatin hubs: Hub
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Hi-C loops: True
Hi-ChIP loops: False
ChIA-PET loops: True
- Compartment:
93% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): True
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Chromatin annotation:
"15_Quies": 54%,
"5_TxWk": 32%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: CHD8, CEBPA, SIN3A, ZFX, DUX4, HNF4G, YY1, ISL1, RAD21, RXRA, PRDM9, MAX, XRCC5, NR2F6, HAND2, CEBPG, CEBPB, NR2F2, TEAD1, TRIM28, SCRT2, NR2F1, ESR1, ZNF652, PHOX2B, CTCF, SP1, HNF4A, TAF1, REST, NOTCH3, BRD4, MAZ, TEAD4, STAG1
- Target gene symbol (double-evidenced CRMs): RCAN1,RUNX1,SMIM11A
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 0
- Number of somatic mutations (non-coding): 0
- Related genes and loops
- Related gene:
ENSG00000205670,
ENSG00000159200,
ENSG00000159216,
- Related loop:
chr21:33975000-34000000~~chr21:34550000-34575000,
chr21:34350000-34375000~~chr21:34550000-34575000,
chr21:34350000-34375000~~chr21:34575000-34600000,
chr21:34543283-34546348~~chr21:34575254-34577002,
chr21:34550000-34575000~~chr21:34850000-34875000,
chr21:7800000-7825000~~chr21:34550000-34575000,
chr21:7800000-7825000~~chr21:34575000-34600000,