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Basic information

CohesinDB ID: CDBP00417793

Locus: chr21-34640014-34641524

Data sourse: GSE93080, ENCSR000HPG, ENCSR000BLY, ENCSR879KXD, GSE206145, GSE206145-NatGen2015, ENCSR000BMY, ENCSR153HNT, GSE68388, GSE73207, GSE50893, GSE165895

Cell type: RPE, GM2630, Fibroblast, GM2610, TF-1, GM12878, IMR-90, SK-N-SH, K-562, HFFc6, HuCC-T1, B-cell

DNA Sequence of binding site: UCSC hg38

Cohesin category

Peak occupancy ratio: 4% samples have this site.

Cell specificity (0: conserved, 1: cell type specific): 0.867

Subunit: NIPBL,SA1,Rad21,SMC1,SA2,Mau2,SMC3

CTCF binding site: CTCF CTCF motif: False

Genomic location: Intergenic

3D genome

TAD boundary: Boundary

Chromatin hubs: Hub

Hi-C loops: True Hi-ChIP loops: True ChIA-PET loops: True

Compartment: 93% Hi-C samples shows Compartment A

Cis-regulatory elements

Enhancer (Fantom5): non-Enhancer

Super enhancer (SEdb): False

Chromatin annotation: "14_ReprPCWk": 31%, "15_Quies": 26%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).

Co-bound Transcriptional factors: FOSL1, PGR, FOXA1, PBX2, HDGF, ATF3, NFIC, RUNX3, ATF4, SMARCE1, PAX5, BACH2, MAF, BCLAF1, TRIM28, RBM39, ETV1, NFE2L2, ZNF217, MLL, USF2, JUN, TCF12, EP300, E4F1, MNT, DPF2, SOX4, E2F6, IRF4, CREB3, RAD51, DDX20, E2F1, TEAD4, KMT2B, RBPJ, EED, GLIS1, POU2F2, BRD1, ZSCAN5D, MYCN, CTBP1, MTA2, SAP130, NBN, ERG, HOXC5, MYC, SMARCA4, ARID1B, RAD21, PROX1, RXRA, FOXK2, BATF3, GABPA, NKX2-1, APC, STAT3, IKZF1, LEF1, NFE2, RCOR1, ARNTL, VDR, CEBPB, STAT5B, CREB1, BMPR1A, GRHL2, EBF3, NFE2L1, ZHX2, SPI1, IRF1, HDAC2, GATA2, FLI1, SMARCA5, RELB, EP400, ATF1, MAFG, SMC1A, HDAC1, SIN3A, ZFX, SMAD3, TRIM22, PRDM10, MEF2A, IRF2, CREBBP, RUNX2, CDK6, NRF1, ARNT, BACH1, TFDP1, PBX4, ATF2, ZNF48, ZEB2, FOXM1, ETV6, PBX3, NR2C1, CDK8, FOS, MED1, DIDO1, MYB, C11orf30, L3MBTL2, STAT5A, MAFK, BCL11A, SP1, NIPBL, NR4A1, USF1, REST, ZBTB7A, ATF7, ASH2L, STAT2, MLLT1, STAG1, NFATC3, MEF2B, KLF13, CBX3, MTA3, EBF1, CREM, RBBP5, E2F8, ZBED1, MAFF, GTF2B, ZBTB33, CDK9, BCL3, ZNF318, CREB3L1, YY1, RELA, TARDBP, JUNB, AHR, ZNF148, ZFP36, SKIL, HIF1A, GATA3, BATF, MGA, TAL1, MAX, GATA1, ZNF143, PLAG1, ZNF592, GFI1B, ZNF687, PKNOX1, TP53, ZNF334, TBX21, BHLHE40, AR, PTRF, TAF1, ZBTB40, ZNF324, RB1, RNF2, IKZF2, BRD4, ILF3, JUND, MAZ, IRF9, ZNF24, ZNF316, FOSL2

Target gene symbol (double-evidenced CRMs): RCAN1,ATP5PO,SMIM11A,MRPS6,ITSN1,CLIC6,AP000311.1

Function elements

Human SNPs: .

Number of somatic mutations (coding): 0

Number of somatic mutations (non-coding): 15

Related genes and loops

Related gene: ENSG00000249209, ENSG00000205726, ENSG00000241837, ENSG00000243927, ENSG00000205670, ENSG00000159200, ENSG00000159212,

eachgene

Deatailed information for cohesin site CDBP00417793