- Basic information
- CohesinDB ID: CDBP00417797
- Locus: chr21-34645493-34646188
-
Data sourse: GSE132649, GSE206145-NatGen2015, GSE67783
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Cell type: T-47D, Fibroblast, HSPC
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 1% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.967
- Subunit: SA1,Rad21
-
CTCF binding site: non-CTCF
CTCF motif: False
- Genomic location: Intergenic
- 3D genome
- TAD boundary: Boundary
- Chromatin hubs: Hub
-
Hi-C loops: True
Hi-ChIP loops: True
ChIA-PET loops: True
- Compartment:
93% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): True
-
Chromatin annotation:
"14_ReprPCWk": 54%,
"15_Quies": 39%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
-
Co-bound Transcriptional factors: .
- Target gene symbol (double-evidenced CRMs): MRPS6,AP000311.1,SMIM11A,ITSN1,RCAN1,ATP5PO
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 0
- Number of somatic mutations (non-coding): 5
- Related genes and loops
- Related gene:
ENSG00000249209,
ENSG00000205726,
ENSG00000241837,
ENSG00000243927,
ENSG00000205670,
ENSG00000159200,
- Related loop:
chr21:33675000-33700000~~chr21:34650000-34675000,
chr21:33900000-33925000~~chr21:34625000-34650000,
chr21:33950000-33975000~~chr21:34625000-34650000,
chr21:34125000-34150000~~chr21:34625000-34650000,
chr21:34150000-34175000~~chr21:34650000-34675000,
chr21:34325000-34350000~~chr21:34625000-34650000,
chr21:34350000-34375000~~chr21:34625000-34650000,
chr21:34500000-34525000~~chr21:34625000-34650000,
chr21:34625000-34650000~~chr21:35925000-35950000,
chr21:34625000-34650000~~chr21:35950000-35975000,
chr21:34640130-34641379~~chr21:34670339-34671972,
chr21:34650000-34675000~~chr21:35925000-35950000,
chr21:7750000-7775000~~chr21:34625000-34650000,
chr21:7800000-7825000~~chr21:34625000-34650000,