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Basic information

CohesinDB ID: CDBP00417798

Locus: chr21-34646765-34647040

Data sourse: GSE67783, ENCSR153HNT, GSE86191

Cell type: K-562, HCT-116, HSPC

DNA Sequence of binding site: UCSC hg38

Cohesin category

Peak occupancy ratio: 1% samples have this site.

Cell specificity (0: conserved, 1: cell type specific): 0.967

Subunit: SA1,Rad21

CTCF binding site: non-CTCF CTCF motif: False

Genomic location: Intergenic

3D genome

TAD boundary: Boundary

Chromatin hubs: Hub

Hi-C loops: True Hi-ChIP loops: True ChIA-PET loops: True

Compartment: 93% Hi-C samples shows Compartment A

Cis-regulatory elements

Enhancer (Fantom5): non-Enhancer

Super enhancer (SEdb): True

Chromatin annotation: "14_ReprPCWk": 48%, "15_Quies": 40%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).

Co-bound Transcriptional factors: POU2F2, CHD8, SMC1A, FOXA2, CEBPA, ZSCAN5D, ZNF263, MYCN, ZFX, PGR, XBP1, WT1, ZSCAN5A, FOXA1, ZNF770, ERG3, ERG2, RELA, CREBBP, OGG1, MYC, ARNT, HIF1A, GATA3, GABPA, APC, MAX, NRIP1, ZNF143, FOS, NR3C1, CEBPB, ETV1, KDM5B, EZH2, TP53, OCA2, ESR1, ZNF334, MYOD1, EGR2, CTCF, JUN, EP300, BCL11A, SPI1, BHLHE40, PAX3-FOXO1, AR, IRF1, GATA2, SIX2, BRD4, CLOCK, MAZ, SMC3, STAG1, TFAP2C

Target gene symbol (double-evidenced CRMs): SMIM11A,RCAN1,MRPS6,ATP5PO,ITSN1,AP000311.1

Function elements

Human SNPs: .

Number of somatic mutations (coding): 0

Number of somatic mutations (non-coding): 1

Related genes and loops

Related gene: ENSG00000249209, ENSG00000205726, ENSG00000241837, ENSG00000243927, ENSG00000205670, ENSG00000159200,

eachgene

Deatailed information for cohesin site CDBP00417798