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Basic information

CohesinDB ID: CDBP00417805

Locus: chr21-34675632-34675953

Data sourse: GSE67783, GSE86191

Cell type: HCT-116, HSPC

DNA Sequence of binding site: UCSC hg38

Cohesin category

Peak occupancy ratio: 0% samples have this site.

Cell specificity (0: conserved, 1: cell type specific): 0.978

Subunit: SA1,Rad21

CTCF binding site: CTCF CTCF motif: False

Genomic location: Intragenic

3D genome

TAD boundary: Boundary

Chromatin hubs: Hub

Hi-C loops: True Hi-ChIP loops: True ChIA-PET loops: True

Compartment: 93% Hi-C samples shows Compartment A

Cis-regulatory elements

Enhancer (Fantom5): non-Enhancer

Super enhancer (SEdb): True

Chromatin annotation: "14_ReprPCWk": 46%, "13_ReprPC": 23%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).

Co-bound Transcriptional factors: FOXO1, TRIM25, PGR, SOX2, MEIS2, XBP1, FOXA1, SUZ12, RING1B, UBTF, MLL4, ZFHX2, PBX2, HDGF, ATF3, BMI1, NFIC, ZBTB5, RUNX3, CHD7, CTCFL, CBFB, MORC2, MECOM, PAX5, ZSCAN4, TP63, MITF, ZNF736, ELF1, BCLAF1, TRIM28, RBM39, SNAI2, TEAD1, COBLL1, ESR1, OCA2, TP73, USF2, ZFP91, CTCF, TCF12, JUN, BAF155, EP300, RYBP, DPF2, PAX8, E2F6, IRF4, RAD51, E2F1, ZNF528, ZNF350, TEAD4, GTF2F1, PDX1, TFAP2C, EED, JARID2, POU2F2, CHD8, BRD1, NANOG, MYCN, POU5F1, TOP2A, RUNX1T1, ZNF263, KDM4C, MTA2, ZSCAN5D, DUX4, ZBTB48, ZSCAN5A, STAT1, SRF, DDX5, NBN, TBP, ERG, ASCL1, OGG1, ZNF341, ETS1, MCM5, MYC, SMARCA4, KDM4A, RAD21, GRHL3, PROX1, RXRA, GABPA, STAT3, XRCC5, NKX3-1, PRDM14, IKZF1, NFE2, INO80, ARNTL, VDR, NR3C1, CEBPB, KMT2A, CREB1, EZH2, GABPB1, PHF8, ZHX2, SPI1, PCBP1, HDAC2, GATA2, GATAD2B, MXD3, ZSCAN29, FLI1, HCFC1, SMARCA5, ZNF766, RELB, ZNF316, ETV5, RUNX1, CBX1, SMC1A, BCL6, EZH2phosphoT487, NKX2-2, SIRT6, IRF3, ZFX, SIN3A, MAFG, PCBP2, NFXL1, CBX8, SP5, ERG3, TRIM22, SMARCC1, ZNF18, MEF2A, ZBTB2, CREBBP, ZNF384, TAF15, CDK6, GATA4, ARNT, BACH1, NRF1, ZBTB10, ZNF48, CBFA2T3, NCAPH2, PBX3, CHD1, CDK8, FOS, MED1, ZEB1, KDM6B, PIAS1, ZNF3, C11orf30, L3MBTL2, MAFK, BCL11A, SP1, GSPT2, HNF4A, REST, ZBTB7A, ARID1A, ZNF479, POU2F3, ATF7, ASH2L, HNRNPLL, PCGF2, CTBP2, BCOR, FOXP1, TCF3, MBD2, AATF, SMC3, STAT2, STAG1, MLLT1, NFATC3, TRP47, CBFA2T2, MEF2B, PPARG, FOXA2, AGO1, EBF1, RBBP5, HDAC6, SS18, TBL1X, E2F8, GTF2B, MAFF, WT1, ZNF574, ZBTB33, TCF7, CDK9, HOXB13, KDM1A, YY1, RELA, TARDBP, BRG1, SP140, ZFP36, HIF1A, PCGF1, SKIL, OTX2, GATA3, BATF, MAF1, MAX, TAL1, NRIP1, GATA1, ZNF143, AGO2, PLAG1, TLE3, KLF4, ZNF592, SP7, CBX2, TCF7L2, NR2F1, KDM5B, TP53, ZNF687, PKNOX1, ZNF334, MYOD1, PHOX2B, T, TBX21, BHLHE40, AR, TAF1, ZBTB40, RXR, EGLN2, HEXIM1, RB1, TFIIIC, HSF1, RNF2, EGR1, BRD4, ZBTB26, IKZF2, NOTCH3, MAZ, AHR

Target gene symbol (double-evidenced CRMs): RUNX1,SETD4,CLIC6

Function elements

Human SNPs: .

Number of somatic mutations (coding): 4

Number of somatic mutations (non-coding): 0

Related genes and loops

Related gene: ENSG00000159212, ENSG00000159216, ENSG00000185917,

eachgene

Deatailed information for cohesin site CDBP00417805