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Basic information

CohesinDB ID: CDBP00417811

Locus: chr21-34687732-34691121

Data sourse: GSE72082, ENCSR000BSB, ENCSR501LQA, ENCSR760NPX, ENCSR000EGW, ENCSR000BLY, ENCSR150EFU, GSE121355, GSE131606, ENCSR330ELC, GSE108869, GSE25021, ENCSR000BUC, ENCSR000DYE, GSE165895, GSE143937, GSE67783, ENCSR000BKV, GSE115250, GSE138405, GSE86191, GSE76893, GSE101921, ENCSR806UKK, GSE51234, GSE120943, GSE206145-NatGen2015, GSE112028, ENCSR199XBQ, ENCSR703TNG, GSE116344, GSE145327, ENCSR895JMI, GSE76815, ENCSR193NSH, ENCSR768DOX, ENCSR879KXD, ENCSR000EHW, GSE85526, ENCSR981FDC, ENCSR247LSH, ENCSR807WAC, ENCSR000EHX, ENCSR620NWG, ENCSR748MVX, ENCSR767DFK, GSE206145, ENCSR495WGO, ENCSR984DZW, ENCSR217ELF, ENCSR000BTQ, GSE105004, ENCSR853VWZ, ENCSR956LGB, ENCSR944ZCT, GSE110061, GSE129526, ENCSR676MJK, GSE111913, ENCSR335RKQ, ENCSR537EFT, ENCSR000EDE, ENCSR153HNT, GSE68388, GSE126990, GSE50893, ENCSR000ECS, ENCSR481YWD

Cell type: RH4, GM10847, GM19240, GP5d, TC-32, HuCC-T1, RPE, GM2630, HMEC, Fibroblast, HEKn, GM12890, HeLa-S3, GM2255, K-562, DKO, HFFc6, GM18526, Monocytes, GM18505, GM2588, SK-N-SH, GM19239, HeLa-Tet-On, GM19193, RT-112, MCF-7, GM12892, Hela-Kyoto, HCT-116, A-549, GM19238, HeLa, CNCC-WT33iPSC, HSPC

DNA Sequence of binding site: UCSC hg38

Cohesin category

Peak occupancy ratio: 34% samples have this site.

Cell specificity (0: conserved, 1: cell type specific): 0.611

Subunit: SA1,Rad21,SMC1,SMC3ac,SA2,SMC3

CTCF binding site: CTCF CTCF motif: False

Genomic location: Intragenic

3D genome

TAD boundary: Boundary

Chromatin hubs: Hub

Hi-C loops: True Hi-ChIP loops: True ChIA-PET loops: True

Compartment: 93% Hi-C samples shows Compartment A

Cis-regulatory elements

Enhancer (Fantom5): non-Enhancer

Super enhancer (SEdb): True

Chromatin annotation: "14_ReprPCWk": 31%, "15_Quies": 22%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).

Co-bound Transcriptional factors: FOXO1, PGR, PPARG, TBL1X, FOXA2, ZFX, XBP1, WT1, FOXA1, BCL3, YY1, RELA, ATF3, RUNX2, GRHL3, PBX4, STAT3, PBX3, NKX3-1, ZNF143, MED1, NR3C1, CEBPB, PDX1, ESR1, CTCF, SPI1, AR, NCOR1, BRD4, SCRT1, TCF3, CLOCK, MAZ, ZNF528, STAG1

Target gene symbol (double-evidenced CRMs): SETD4,CLIC6,RUNX1

Function elements

Human SNPs: .

Number of somatic mutations (coding): 40

Number of somatic mutations (non-coding): 0

Related genes and loops

Related gene: ENSG00000159212, ENSG00000159216, ENSG00000185917,

eachgene

Deatailed information for cohesin site CDBP00417811