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Basic information

CohesinDB ID: CDBP00417813

Locus: chr21-34697770-34698335

Data sourse: GSE116344, GSE165895

Cell type: RH4, HFFc6

DNA Sequence of binding site: UCSC hg38

Cohesin category

Peak occupancy ratio: 0% samples have this site.

Cell specificity (0: conserved, 1: cell type specific): 0.978

Subunit: Rad21,SMC1

CTCF binding site: CTCF CTCF motif: False

Genomic location: Intragenic

3D genome

TAD boundary: Boundary

Chromatin hubs: Hub

Hi-C loops: True Hi-ChIP loops: True ChIA-PET loops: True

Compartment: 93% Hi-C samples shows Compartment A

Cis-regulatory elements

Enhancer (Fantom5): non-Enhancer

Super enhancer (SEdb): False

Chromatin annotation: "15_Quies": 55%, "14_ReprPCWk": 26%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).

Co-bound Transcriptional factors: CHD8, ZSCAN5D, HDAC1, ZNF263, POU5F1, ID3, ZFX, NME2, XBP1, SOX2, ZFP3, PCBP2, SMAD3, ESR2, ZNF662, SUZ12, MCM2, PHB2, ZKSCAN1, ERG, RELA, HDGF, TARDBP, ZNF148, MYC, MCM5, RFX1, ZNF184, RAD21, MCM3, NFIB, ZBTB5, CHD7, PROX1, ZNF311, ATF2, ZEB2, ZNF8, XRCC5, ZNF143, IKZF1, MTA1, MITF, ZNF639, ZNF467, PLAG1, ZEB1, TEAD1, BCLAF1, NCOA3, ZNF512, MCM7, NR2F1, MLLT1, LMO2, KDM5B, PKNOX1, ARHGAP35, ESR1, USF2, CTCF, ELF3, USF1, JUN, E4F1, DPF2, HDAC2, ZBTB40, GATAD2B, ZNF366, ATF7, FLI1, POU2F3, IKZF2, JUND, SMARCA5, ZNF512B, AFF1, BCOR, ZNF776, TEAD4, ZNF24, EHMT2, TFAP2C

Target gene symbol (double-evidenced CRMs): CLIC6,RUNX1,SETD4

Function elements

Human SNPs: .

Number of somatic mutations (coding): 6

Number of somatic mutations (non-coding): 0

Related genes and loops

Related gene: ENSG00000159212, ENSG00000159216, ENSG00000185917,

eachgene

Deatailed information for cohesin site CDBP00417813