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Basic information

CohesinDB ID: CDBP00417815

Locus: chr21-34701028-34701356

Data sourse: GSE206145, GSE206145-NatGen2015, GSE67783

Cell type: RPE, Fibroblast, HSPC

DNA Sequence of binding site: UCSC hg38

Cohesin category

Peak occupancy ratio: 1% samples have this site.

Cell specificity (0: conserved, 1: cell type specific): 0.967

Subunit: SA1,Rad21,SA2

CTCF binding site: CTCF CTCF motif: False

Genomic location: Intragenic

3D genome

TAD boundary: Boundary

Chromatin hubs: Hub

Hi-C loops: True Hi-ChIP loops: True ChIA-PET loops: True

Compartment: 93% Hi-C samples shows Compartment A

Cis-regulatory elements

Enhancer (Fantom5): non-Enhancer

Super enhancer (SEdb): False

Chromatin annotation: "15_Quies": 55%, "14_ReprPCWk": 34%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).

Co-bound Transcriptional factors: RUNX1, TRP47, PGR, FOXA2, ZFX, CTBP1, WT1, FOXA1, ERG3, ERG2, HOXB13, ZNF28, ERG, YY1, ZNF384, OGG1, RUNX2, RUNX3, ZIC2, NKX2-1, GATA3, BATF, MGA, STAT3, MAX, NRIP1, NKX3-1, ZNF736, NR3C1, CEBPB, ZEB1, CREB1, KDM5B, ESR1, NCOA1, L3MBTL2, EGR2, BAF155, E4F1, MNT, AR, ZBTB40, GATA2, ARID1A, BRD4, MAZ, TEAD4

Target gene symbol (double-evidenced CRMs): SETD4,CLIC6,RUNX1

Function elements

Human SNPs: .

Number of somatic mutations (coding): 4

Number of somatic mutations (non-coding): 0

Related genes and loops

Related gene: ENSG00000159212, ENSG00000159216, ENSG00000185917,

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Deatailed information for cohesin site CDBP00417815