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Basic information

CohesinDB ID: CDBP00417817

Locus: chr21-34705086-34705452

Data sourse: GSE206145-NatGen2015, GSE67783

Cell type: Fibroblast, HSPC

DNA Sequence of binding site: UCSC hg38

Cohesin category

Peak occupancy ratio: 1% samples have this site.

Cell specificity (0: conserved, 1: cell type specific): 0.978

Subunit: SA1,Rad21,SA2

CTCF binding site: non-CTCF CTCF motif: False

Genomic location: Intragenic

3D genome

TAD boundary: Boundary

Chromatin hubs: Hub

Hi-C loops: True Hi-ChIP loops: True ChIA-PET loops: True

Compartment: 93% Hi-C samples shows Compartment A

Cis-regulatory elements

Enhancer (Fantom5): non-Enhancer

Super enhancer (SEdb): False

Chromatin annotation: "15_Quies": 35%, "14_ReprPCWk": 27%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).

Co-bound Transcriptional factors: FOXO1, PAX7, PGR, SMARCA2, CEBPA, MYCN, PPARG, CHD2, POU5F1, ZFX, WT1, STAT1, FOXA1, CBX8, HOXB13, SMARCC1, KDM1A, YY1, RELA, JUNB, ATF3, MYC, GATA4, ISL1, TAL1, GATA3, STAT3, PBX3, IRF9, MAX, FOXM1, FOS, RCOR1, TP63, HAND2, MED1, ZNF736, GATA1, NR3C1, CEBPG, CEBPB, KLF4, ELF1, SNAI2, EZH2, ESR1, TP53, TP73, PITX3, NFKB1, EBF3, USF2, PHOX2B, JUN, TCF12, CTCF, EP300, SPI1, NR4A1, AR, GATA6, REST, GATA2, ZNF479, POU2F3, FLI1, RNF2, BRD4, BCOR, MAZ, ZNF350, MRTFB, TEAD4, STAG1, AHR

Target gene symbol (double-evidenced CRMs): CLIC6,SETD4,RUNX1

Function elements

Human SNPs: .

Number of somatic mutations (coding): 12

Number of somatic mutations (non-coding): 0

Related genes and loops

Related gene: ENSG00000159212, ENSG00000159216, ENSG00000185917,

eachgene

Deatailed information for cohesin site CDBP00417817