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Basic information

CohesinDB ID: CDBP00417820

Locus: chr21-34712749-34713096

Data sourse: ENCSR000BLD, GSE206145-GSE177045, GSE72082, ENCSR000FAD, ENCSR000EGW, ENCSR000EDW, ENCSR000DYE, ENCSR000EFJ, ENCSR000DZP, ENCSR000EAC, ENCSR000BKV, GSE120943, GSE98367, ENCSR000BLS, GSE206145, ENCSR000ECE, ENCSR000BMY, ENCSR635OSG, ENCSR000HPG, ENCSR000ECS, ENCSR481YWD

Cell type: MCF-7, H1-hESC, Monocytes, Hep-G2, GM12878, A-549, HeLa-S3, IMR-90, K-562, Liver, Macrophage, B-cell

DNA Sequence of binding site: UCSC hg38

Cohesin category

Peak occupancy ratio: 7% samples have this site.

Cell specificity (0: conserved, 1: cell type specific): 0.867

Subunit: Mau2,SMC3,Rad21,SMC1

CTCF binding site: non-CTCF CTCF motif: False

Genomic location: Intragenic

3D genome

TAD boundary: Boundary

Chromatin hubs: Hub

Hi-C loops: True Hi-ChIP loops: True ChIA-PET loops: True

Compartment: 93% Hi-C samples shows Compartment A

Cis-regulatory elements

Enhancer (Fantom5): non-Enhancer

Super enhancer (SEdb): False

Chromatin annotation: "15_Quies": 49%, "14_ReprPCWk": 38%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).

Co-bound Transcriptional factors: ARNTL, CREBBP, CHD8, MYC, TRIM28, MYCN, ZFX, NME2, ARNT, XBP1, ZBTB48, PCBP2, ZNF749, NCOA2, CTCF, YY1

Target gene symbol (double-evidenced CRMs): RUNX1,CLIC6,SETD4

Function elements

Human SNPs: .

Number of somatic mutations (coding): 4

Number of somatic mutations (non-coding): 0

Related genes and loops

Related gene: ENSG00000159212, ENSG00000159216, ENSG00000185917,

eachgene

Deatailed information for cohesin site CDBP00417820