- Basic information
- CohesinDB ID: CDBP00417821
- Locus: chr21-34715391-34715920
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Data sourse: GSE67783, GSE50893, ENCSR000BMY, ENCSR153HNT
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Cell type: K-562, GM12878, HSPC, GM18505
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 1% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.956
- Subunit: SA1,Rad21
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CTCF binding site: non-CTCF
CTCF motif: False
- Genomic location: TES
- 3D genome
- TAD boundary: Boundary
- Chromatin hubs: Hub
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Hi-C loops: True
Hi-ChIP loops: True
ChIA-PET loops: True
- Compartment:
93% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): False
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Chromatin annotation:
"15_Quies": 44%,
"14_ReprPCWk": 37%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: FOXO1, PGR, XBP1, KDM4B, FOXA1, PBX2, UBTF, HDGF, NFIC, RUNX3, PAX5, ZSCAN4, ELF1, BCLAF1, ETV1, RBM39, NFE2L2, OCA2, CTCF, JUN, EP300, E4F1, PYGO2, IRF4, TRIM24, CREB3, TEAD4, EHMT2, EED, POU2F2, CHD8, ZNF263, RUNX1T1, ID3, CTBP1, ZBTB48, STAT1, DDX5, ERG2, TBP, ERG, ETS1, MYC, EZH1, ARID1B, FOXP2, GRHL3, BATF3, GABPA, STAT3, IKZF1, RCOR1, TERF2, LEF1, STAT5B, CREB1, ZBTB11, EZH2, BMPR1A, GABPB1, SPI1, IRF1, FLI1, HCFC1, NR2C2, NCOA2, ATF1, RUNX1, BCL6, SMC1A, HDAC1, ZFX, ERG3, ZBTB2, IRF2, NOTCH1, RUNX2, ARNT, NRF1, ATF2, PRDM9, ZEB2, HMBOX1, ETV6, NR2C1, DIDO1, VEZF1, NCOA1, C11orf30, L3MBTL2, BCL11A, SP1, NR4A1, ZBTB7A, POU2F3, ATF7, BCOR, FOXP1, STAT2, ILK, STAG1, MLLT1, CBX3, MTA3, EBF1, CREM, ZNF692, YY1, RELA, TARDBP, JUNB, ZNF148, NEUROD1, ZFP36, BATF, TAL1, MAX, SPIB, NRIP1, GATA1, GFI1B, NR2F2, TP53, ZSCAN22, MYOD1, AR, ZBTB40, EGR1, HSF1, MYNN, IKZF2, BRD4, JUND, ILF3, MAZ, ZNF24
- Target gene symbol (double-evidenced CRMs): CLIC6,SETD4,RUNX1
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 0
- Number of somatic mutations (non-coding): 0
- Related genes and loops
- Related gene:
ENSG00000159212,
ENSG00000159216,
ENSG00000185917,
- Related loop:
chr21:34700000-34725000~~chr21:34825000-34850000,
chr21:34700000-34725000~~chr21:34850000-34875000,
chr21:34700000-34725000~~chr21:35025000-35050000,
chr21:34700000-34725000~~chr21:35375000-35400000,
chr21:34700000-34725000~~chr21:35400000-35425000,
chr21:34700000-34725000~~chr21:35500000-35525000,
chr21:34700000-34725000~~chr21:35825000-35850000,
chr21:34700000-34725000~~chr21:35925000-35950000,
chr21:34700000-34725000~~chr21:35975000-36000000,
chr21:34700000-34725000~~chr21:36025000-36050000,
chr21:34718892-34720426~~chr21:35507719-35509586,