- Basic information
- CohesinDB ID: CDBP00417826
- Locus: chr21-34721618-34723787
-
Data sourse: ENCSR000BLD, GSE206145-GSE177045, GSE104888, ENCSR230ZWH, ENCSR000FAD, GSE72082, ENCSR000BSB, ENCSR000EGW, ENCSR000BLY, GSE105028, GSE121355, GSE103477, GSE111537, GSE131606, GSE108869, ENCSR000EDW, GSE25021, ENCSR917QNE, ENCSR000BTU, GSE93080, ENCSR000DZP, ENCSR000EAC, GSE143937, ENCSR000BKV, GSE115250, GSE138405, GSE67783, GSE86191, GSE76893, GSE101921, GSE152721, GSE51234, GSE120943, GSE206145-NatGen2015, GSE112028, GSE130135, ENCSR703TNG, GSE106870, GSE116344, GSE145327, GSE94872, ENCSR000EEG, ENCSR338DUC, GSE98367, ENCSR879KXD, ENCSR000BLS, GSE206145, ENCSR000ECE, ENCSR981FDC, ENCSR000BMY, GSE97394, GSE55407, ENCSR000BTQ, GSE105004, ENCSR167MTG, GSE131956, GSE110061, GSE129526, GSE111913, GSE155324, GSE38411, ENCSR054FKH, ENCSR000EDE, ENCSR153HNT, GSE68388, GSE83726, GSE126990, GSE50893, GSE126755, ENCSR000ECS, GSE131577
-
Cell type: MDM, RH4, GM10847, GM2610, CVB-hiPSC, GM19240, OCI-AML-3, HSPC, CVI-hiPSC, Liver, GP5d, TC-32, HuCC-T1, B-cell, H9-hESC, GM2630, RPE, Fibroblast, THP-1, Ishikawa, GM12890, HeLa-S3, GM2255, BCBL-1, K-562, GM18486, DKO, GM18526, H1-hESC, SNYDER, Monocytes, GM18505, Lymphoblast, GM12878, GM12891, GM2588, GBM39, SK-N-SH, GM19239, HeLa-Tet-On, GM19193, RT-112, HAP1, GM19099, HUES64, Macrophage, GM12892, MCF-7, Hela-Kyoto, HCT-116, HL-60, HEK293T, Hep-G2, MCF-10A, A-549, HUVEC, HCAEC, GM19238, HeLa, Neutrophil, GM18951
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 40% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.311
- Subunit: SA1,Rad21,SMC1,SA2,SMC3
-
CTCF binding site: CTCF
CTCF motif: True
- Genomic location: TES
- 3D genome
- TAD boundary: Boundary
- Chromatin hubs: Hub
-
Hi-C loops: True
Hi-ChIP loops: True
ChIA-PET loops: True
- Compartment:
93% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): False
-
Chromatin annotation:
"15_Quies": 43%,
"14_ReprPCWk": 31%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
-
Co-bound Transcriptional factors: MITF, PGR, NCOA3, TERF1, MYCN, DDX5, ZFX, SP140, ESR1, WT1, ZSCAN5A, SRF, CBX8, STAT3, CTCF, BCL11A, STAG1, AHR
- Target gene symbol (double-evidenced CRMs): SETD4,CLIC6,RUNX1
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 0
- Number of somatic mutations (non-coding): 12
- Related genes and loops
- Related gene:
ENSG00000159212,
ENSG00000159216,
ENSG00000185917,
- Related loop:
chr21:34350000-34375000~~chr21:34725000-34750000,
chr21:34700000-34725000~~chr21:34825000-34850000,
chr21:34700000-34725000~~chr21:34850000-34875000,
chr21:34700000-34725000~~chr21:35025000-35050000,
chr21:34700000-34725000~~chr21:35375000-35400000,
chr21:34700000-34725000~~chr21:35400000-35425000,
chr21:34700000-34725000~~chr21:35500000-35525000,
chr21:34700000-34725000~~chr21:35825000-35850000,
chr21:34700000-34725000~~chr21:35925000-35950000,
chr21:34700000-34725000~~chr21:35975000-36000000,
chr21:34700000-34725000~~chr21:36025000-36050000,
chr21:34718892-34720426~~chr21:35507719-35509586,
chr21:34722039-34723826~~chr21:35507813-35509465,
chr21:34722101-34723694~~chr21:35615336-35617186,
chr21:34725000-34750000~~chr21:34825000-34850000,
chr21:34725000-34750000~~chr21:34850000-34875000,
chr21:34725000-34750000~~chr21:34875000-34900000,
chr21:34725000-34750000~~chr21:35025000-35050000,
chr21:34725000-34750000~~chr21:35200000-35225000,
chr21:34725000-34750000~~chr21:35400000-35425000,
chr21:34725000-34750000~~chr21:35500000-35525000,
chr21:34725000-34750000~~chr21:35600000-35625000,
chr21:34725000-34750000~~chr21:35825000-35850000,
chr21:34725000-34750000~~chr21:35925000-35950000,
chr21:34725000-34750000~~chr21:36025000-36050000,