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Basic information

CohesinDB ID: CDBP00417829

Locus: chr21-34728212-34729038

Data sourse: GSE206145-GSE177045, ENCSR230ZWH, GSE72082, GSE76893, ENCSR153HNT, ENCSR703TNG, GSE115602

Cell type: K-562, Liver, MCF-7

DNA Sequence of binding site: UCSC hg38

Cohesin category

Peak occupancy ratio: 3% samples have this site.

Cell specificity (0: conserved, 1: cell type specific): 0.967

Subunit: NIPBL,SA1,Rad21,SMC1,Mau2

CTCF binding site: non-CTCF CTCF motif: False

Genomic location: TES,Intragenic

3D genome

TAD boundary: Boundary

Chromatin hubs: Hub

Hi-C loops: True Hi-ChIP loops: True ChIA-PET loops: True

Compartment: 93% Hi-C samples shows Compartment A

Cis-regulatory elements

Enhancer (Fantom5): non-Enhancer

Super enhancer (SEdb): False

Chromatin annotation: "15_Quies": 51%, "14_ReprPCWk": 32%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).

Co-bound Transcriptional factors: PGR, SOX2, FOXA1, TFAP4, BMI1, CHD7, PRDM1, ZNF444, SMARCE1, HDAC3, KLF5, TEAD1, ELF1, ETV1, ZNF217, ESR1, LMO2, JUN, TCF12, BAF155, EP300, LMO1, SOX9, GATA6, DPF2, MED12, E2F1, TFAP2C, NANOG, POU5F1, CTBP1, DUX4, ERG, MYC, RAD21, RXRA, NKX2-1, BATF3, GABPA, STAT3, APC, NKX3-1, RCOR1, NR3C1, ESRRA, CEBPB, CREB1, EZH2, GRHL2, TRPS1, EHF, ZSCAN2, GATA2, NCOA2, RUNX1, SMC1A, SIN3A, ZFX, SMAD3, CBX8, ZXDC, CREBBP, RUNX2, GR, ARNT, NFIB, SOX11, FOXM1, FOS, MED1, SCRT2, PIAS1, NCOA1, NIPBL, TFAP2A, SP1, HNF4A, BCL11A, ARID1A, ASH2L, CTBP2, FOXP1, NCOR2, STAG2, FOXA2, ESR2, HOXB13, ZNF19, RELA, NEUROD1, HIF1A, GATA3, MAX, NRIP1, GATA1, MTA1, TLE3, KLF4, ZNF592, NCOA3, NR2F2, KDM5B, ZNF687, TP53, ZNF334, NFKB1, AR, EGLN2, BRD4, SCRT1, JUND, CUX1, AHR, FOSL2

Target gene symbol (double-evidenced CRMs): SMIM11A,RUNX1,SETD4

Function elements

Human SNPs: .

Number of somatic mutations (coding): 0

Number of somatic mutations (non-coding): 0

Related genes and loops

Related gene: ENSG00000205670, ENSG00000159216, ENSG00000185917,

eachgene

Deatailed information for cohesin site CDBP00417829