- Basic information
- CohesinDB ID: CDBP00417831
- Locus: chr21-34732355-34732995
-
Data sourse: GSE85526, GSE206145-NatGen2015, ENCSR879KXD, GSE165895
-
Cell type: K-562, Fibroblast, HEKn, HFFc6
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 1% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.956
- Subunit: Mau2,Rad21,SMC1
-
CTCF binding site: CTCF
CTCF motif: False
- Genomic location: TSS
- 3D genome
- TAD boundary: Boundary
- Chromatin hubs: Hub
-
Hi-C loops: True
Hi-ChIP loops: True
ChIA-PET loops: True
- Compartment:
93% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): False
-
Chromatin annotation:
"15_Quies": 53%,
"14_ReprPCWk": 30%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
-
Co-bound Transcriptional factors: FOSL1, PGR, SMC1A, FOXA2, MEIS1, ID3, MEIS2, CTBP1, SMAD3, ZNF823, PBX2, KDM1A, JUNB, ATF3, MYC, GATA4, PBX4, GATA3, HMBOX1, STAT3, PBX3, FOS, MED1, KLF4, CEBPB, ZNF750, ESR1, JUN, BCL11A, SPI1, EHF, AR, GATA2, YAP1, BRD4, JUND, ATF1
- Target gene symbol (double-evidenced CRMs): SETD4,SMIM11A,RUNX1
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 0
- Number of somatic mutations (non-coding): 0
- Related genes and loops
- Related gene:
ENSG00000205670,
ENSG00000159216,
ENSG00000185917,
- Related loop:
chr21:34350000-34375000~~chr21:34725000-34750000,
chr21:34725000-34750000~~chr21:34825000-34850000,
chr21:34725000-34750000~~chr21:34850000-34875000,
chr21:34725000-34750000~~chr21:34875000-34900000,
chr21:34725000-34750000~~chr21:35025000-35050000,
chr21:34725000-34750000~~chr21:35200000-35225000,
chr21:34725000-34750000~~chr21:35400000-35425000,
chr21:34725000-34750000~~chr21:35500000-35525000,
chr21:34725000-34750000~~chr21:35600000-35625000,
chr21:34725000-34750000~~chr21:35825000-35850000,
chr21:34725000-34750000~~chr21:35925000-35950000,
chr21:34725000-34750000~~chr21:36025000-36050000,