- Basic information
- CohesinDB ID: CDBP00417838
- Locus: chr21-34749135-34749722
-
Data sourse: GSE111913, GSE86191, GSE98367
-
Cell type: RT-112, HCT-116, Macrophage
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 1% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.967
- Subunit: Rad21,SMC1
-
CTCF binding site: CTCF
CTCF motif: False
- Genomic location: TSS
- 3D genome
- TAD boundary: Boundary
- Chromatin hubs: Hub
-
Hi-C loops: True
Hi-ChIP loops: True
ChIA-PET loops: True
- Compartment:
93% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): False
-
Chromatin annotation:
"15_Quies": 64%,
"14_ReprPCWk": 28%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
-
Co-bound Transcriptional factors: HMG20A, FOXA2, CEBPA, SOX13, ZFX, HNF1A, FOXA1, TCF7, RXRB, SMARCC1, KDM1A, RARA, ZNF133, SP140, PBX4, PRDM9, NR2F6, CEBPG, CEBPB, NR3C1, TEAD1, RCOR2, TP53, HNF1B, USF1, SPI1, EP300, TFE3, BHLHE40, HNF4A, SOX5, AR, HDAC2, FOXA3, ZNF175, GATAD2A
- Target gene symbol (double-evidenced CRMs): SETD4,SMIM11A,RUNX1
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 0
- Number of somatic mutations (non-coding): 4
- Related genes and loops
- Related gene:
ENSG00000205670,
ENSG00000159216,
ENSG00000185917,
- Related loop:
chr21:34350000-34375000~~chr21:34725000-34750000,
chr21:34350000-34375000~~chr21:34750000-34775000,
chr21:34725000-34750000~~chr21:34825000-34850000,
chr21:34725000-34750000~~chr21:34850000-34875000,
chr21:34725000-34750000~~chr21:34875000-34900000,
chr21:34725000-34750000~~chr21:35025000-35050000,
chr21:34725000-34750000~~chr21:35200000-35225000,
chr21:34725000-34750000~~chr21:35400000-35425000,
chr21:34725000-34750000~~chr21:35500000-35525000,
chr21:34725000-34750000~~chr21:35600000-35625000,
chr21:34725000-34750000~~chr21:35825000-35850000,
chr21:34725000-34750000~~chr21:35925000-35950000,
chr21:34725000-34750000~~chr21:36025000-36050000,
chr21:34743262-34746775~~chr21:35399352-35402534,
chr21:34743262-34746775~~chr21:35507734-35509545,
chr21:34743265-34746806~~chr21:35507719-35509586,
chr21:34743512-34746717~~chr21:35399678-35401615,
chr21:34744447-34746791~~chr21:35399674-35401602,
chr21:34744447-34746791~~chr21:35507750-35509614,
chr21:34744498-34746753~~chr21:35399738-35401521,
chr21:34744530-34746777~~chr21:34887476-34892097,
chr21:34744530-34746777~~chr21:35399848-35401817,
chr21:34744530-34746777~~chr21:35614293-35617009,
chr21:34744539-34746791~~chr21:35399305-35401597,
chr21:34744539-34746791~~chr21:35507739-35509404,
chr21:34744552-34746822~~chr21:35507858-35509465,
chr21:34744561-34746765~~chr21:34887508-34892091,
chr21:34744561-34746765~~chr21:35399885-35401612,
chr21:34744561-34746765~~chr21:35615361-35617172,
chr21:34744567-34746780~~chr21:35188780-35191250,
chr21:34744567-34746780~~chr21:35399613-35401825,
chr21:34744567-34746780~~chr21:35615336-35617206,
chr21:34744574-34746750~~chr21:35507769-35509498,
chr21:34744580-34747072~~chr21:35399810-35401595,
chr21:34744581-34746732~~chr21:35399641-35401580,
chr21:34744589-34746918~~chr21:35399325-35401608,
chr21:34744589-34746918~~chr21:35507735-35509518,
chr21:34744589-34746918~~chr21:35615292-35617215,
chr21:34744610-34746779~~chr21:35507406-35509556,
chr21:34744610-34746779~~chr21:35602844-35604275,
chr21:34744631-34746764~~chr21:35399233-35401565,
chr21:34744640-34746731~~chr21:35399927-35401584,
chr21:34744749-34746554~~chr21:35399692-35401398,
chr21:34744771-34746620~~chr21:35399417-35401599,
chr21:34744771-34746620~~chr21:35615456-35617044,
chr21:34744773-34746587~~chr21:35399649-35401523,
chr21:34744777-34746623~~chr21:35507640-35509736,
chr21:34744780-34746750~~chr21:35399619-35401488,
chr21:34744787-34746612~~chr21:35507728-35509232,
chr21:34744787-34746612~~chr21:35615562-35617011,
chr21:34744790-34746552~~chr21:35399665-35401305,
chr21:34744790-34746552~~chr21:35507844-35509236,
chr21:34744815-34746785~~chr21:35398829-35401607,
chr21:34744820-34746780~~chr21:35507828-35509473,
chr21:34744836-34747063~~chr21:35398212-35401570,
chr21:34744840-34746785~~chr21:35399637-35401641,
chr21:34744840-34746785~~chr21:35507813-35509465,
chr21:34744840-34746785~~chr21:35615343-35617201,
chr21:34744848-34746795~~chr21:35399380-35401604,
chr21:34744855-34746749~~chr21:34887552-34891083,
chr21:34744866-34746754~~chr21:34887518-34891075,
chr21:34744866-34746754~~chr21:35507843-35509232,
chr21:34744879-34746754~~chr21:34888325-34891071,
chr21:34744884-34746937~~chr21:35399872-35401634,
chr21:34744884-34746937~~chr21:35615517-35617148,
chr21:34744887-34746720~~chr21:35399838-35401610,
chr21:34744917-34746726~~chr21:35399887-35401622,
chr21:34744927-34746749~~chr21:35507798-35509438,
chr21:34745037-34746426~~chr21:35399955-35401288,
chr21:34750000-34775000~~chr21:34850000-34875000,
chr21:34750000-34775000~~chr21:34875000-34900000,
chr21:34750000-34775000~~chr21:35000000-35025000,
chr21:34750000-34775000~~chr21:35400000-35425000,
chr21:34750000-34775000~~chr21:35500000-35525000,
chr21:34750000-34775000~~chr21:35600000-35625000,
chr21:34750000-34775000~~chr21:35775000-35800000,
chr21:34750000-34775000~~chr21:35825000-35850000,
chr21:34750000-34775000~~chr21:35925000-35950000,
chr21:34750000-34775000~~chr21:36000000-36025000,
chr21:34750000-34775000~~chr21:36025000-36050000,