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Basic information

CohesinDB ID: CDBP00417844

Locus: chr21-34758515-34759013

Data sourse: ENCSR000BLD, GSE67783, GSE86191, GSE111913, GSE206145-NatGen2015, ENCSR153HNT, GSE68388, GSE116344

Cell type: H1-hESC, Fibroblast, HCT-116, RH4, RT-112, K-562, HSPC, HuCC-T1

DNA Sequence of binding site: UCSC hg38

Cohesin category

Peak occupancy ratio: 2% samples have this site.

Cell specificity (0: conserved, 1: cell type specific): 0.911

Subunit: SA1,Rad21,SA2,SMC1

CTCF binding site: non-CTCF CTCF motif: False

Genomic location: Intragenic

3D genome

TAD boundary: non-Boundary

Chromatin hubs: Hub

Hi-C loops: True Hi-ChIP loops: False ChIA-PET loops: True

Compartment: 91% Hi-C samples shows Compartment A

Cis-regulatory elements

Enhancer (Fantom5): non-Enhancer

Super enhancer (SEdb): False

Chromatin annotation: "15_Quies": 66%, "14_ReprPCWk": 29%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).

Co-bound Transcriptional factors: MYCN, POU5F1, ZFX, ZSCAN16, ZBTB48, WT1, DUX4, FOXA1, ZSCAN5A, RAD21, SP140, HIF1A, SOX11, HMBOX1, XRCC5, TEAD1, NR2F2, NR2F1, ESR1, GRHL2, CTCF, AR, PAX3-FOXO1, MAZ, TEAD4, STAG1, TFAP2C

Target gene symbol (double-evidenced CRMs): SMIM11A,SETD4,RUNX1

Function elements

Human SNPs: .

Number of somatic mutations (coding): 0

Number of somatic mutations (non-coding): 0

Related genes and loops

Related gene: ENSG00000205670, ENSG00000159216, ENSG00000185917,

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Deatailed information for cohesin site CDBP00417844