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Basic information

CohesinDB ID: CDBP00417845

Locus: chr21-34760153-34761814

Data sourse: GSE67783, GSE86191, GSE110061, GSE111913, GSE206145, GSE206145-NatGen2015, ENCSR153HNT

Cell type: RPE, Fibroblast, HCT-116, RT-112, K-562, HSPC

DNA Sequence of binding site: UCSC hg38

Cohesin category

Peak occupancy ratio: 2% samples have this site.

Cell specificity (0: conserved, 1: cell type specific): 0.933

Subunit: SA1,Rad21,SA2,SMC1

CTCF binding site: CTCF CTCF motif: False

Genomic location: Intragenic

3D genome

TAD boundary: non-Boundary

Chromatin hubs: Hub

Hi-C loops: True Hi-ChIP loops: False ChIA-PET loops: True

Compartment: 91% Hi-C samples shows Compartment A

Cis-regulatory elements

Enhancer (Fantom5): non-Enhancer

Super enhancer (SEdb): False

Chromatin annotation: "15_Quies": 69%, "14_ReprPCWk": 25%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).

Co-bound Transcriptional factors: RUNX1, NCOA2, POU2F2, BCL6, ZNF316, MAFG, MYCN, POU5F1, ZNF263, CRY1, ZFX, CTBP1, XBP1, ZBTB48, WT1, MAFF, FOXA1, ESR2, PBX2, HOXB13, YY1, RELA, CREBBP, RUNX2, MYC, CTCFL, ARNT, GRHL3, HIF1A, GATA3, PRDM9, PGR, STAT3, TP63, NKX3-1, PRDM14, NRIP1, FOS, TLE3, ZFP69B, NCOA3, KLF6, EZH2, ZNF3, TP53, OCA2, ESR1, C11orf30, ZNF334, ZSCAN22, MYOD1, CTCF, RBM22, MAFK, BAF155, ZHX2, EP300, AR, GATA2, ATF7, SREBF1, MAZ, SMC3, STAG1, AHR, EED

Target gene symbol (double-evidenced CRMs): RUNX1,SETD4,SMIM11A

Function elements

Human SNPs: .

Number of somatic mutations (coding): 0

Number of somatic mutations (non-coding): 0

Related genes and loops

Related gene: ENSG00000205670, ENSG00000159216, ENSG00000185917,

eachgene

Deatailed information for cohesin site CDBP00417845