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Basic information

CohesinDB ID: CDBP00417855

Locus: chr21-34780128-34780588

Data sourse: GSE206145-NatGen2015, GSE25021, GSE67783

Cell type: MCF-7, Fibroblast, HSPC

DNA Sequence of binding site: UCSC hg38

Cohesin category

Peak occupancy ratio: 1% samples have this site.

Cell specificity (0: conserved, 1: cell type specific): 0.967

Subunit: SA1

CTCF binding site: CTCF CTCF motif: False

Genomic location: TES

3D genome

TAD boundary: Boundary

Chromatin hubs: Hub

Hi-C loops: True Hi-ChIP loops: True ChIA-PET loops: True

Compartment: 91% Hi-C samples shows Compartment A

Cis-regulatory elements

Enhancer (Fantom5): non-Enhancer

Super enhancer (SEdb): False

Chromatin annotation: "15_Quies": 73%, "14_ReprPCWk": 16%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).

Co-bound Transcriptional factors: RUNX1, SMC1A, TOP2A, SS18, ZFX, HNF1A, ZBTB48, ZSCAN5A, WT1, FOXA1, DUX4, DDX5, HOXB13, ERG, YY1, ZNF384, RUNX2, SMARCA4, ZNF362, ARNT, HIF1A, RXRA, ATF2, STAT3, CEBPB, TEAD3, TEAD1, TRIM28, EZH2, ESR1, HNF1B, CTCF, JUN, ELF3, SPI1, SP1, ZHX2, AR, IRF1, ARID2, ARID1A, TRIM24, SIX2, ATF7, JUND, SMC3, ZNF316

Target gene symbol (double-evidenced CRMs): SMIM11A,CLIC6,RUNX1

Function elements

Human SNPs: .

Number of somatic mutations (coding): 0

Number of somatic mutations (non-coding): 0

Related genes and loops

Related gene: ENSG00000205670, ENSG00000159212, ENSG00000159216,

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Deatailed information for cohesin site CDBP00417855