- Basic information
- CohesinDB ID: CDBP00417856
- Locus: chr21-34781697-34781958
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Data sourse: GSE67783, ENCSR153HNT, GSE86191
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Cell type: K-562, HCT-116, HSPC
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 1% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.967
- Subunit: SA1,Rad21
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CTCF binding site: CTCF
CTCF motif: False
- Genomic location: TES
- 3D genome
- TAD boundary: Boundary
- Chromatin hubs: Hub
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Hi-C loops: True
Hi-ChIP loops: True
ChIA-PET loops: True
- Compartment:
91% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): False
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Chromatin annotation:
"15_Quies": 76%,
"14_ReprPCWk": 14%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: RUNX1, SMC1A, TOP2A, SS18, ZFX, HNF1A, ZBTB48, ZSCAN5A, WT1, FOXA1, DUX4, DDX5, HOXB13, ERG, YY1, ZNF384, RUNX2, SMARCA4, ZNF362, ARNT, HIF1A, RXRA, ATF2, STAT3, CEBPB, TEAD3, TEAD1, TRIM28, EZH2, ESR1, HNF1B, CTCF, JUN, ELF3, SPI1, SP1, ZHX2, AR, IRF1, ARID2, ARID1A, TRIM24, SIX2, ATF7, JUND, SMC3, ZNF316
- Target gene symbol (double-evidenced CRMs): SMIM11A,RUNX1,CLIC6
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 0
- Number of somatic mutations (non-coding): 0
- Related genes and loops
- Related gene:
ENSG00000205670,
ENSG00000159212,
ENSG00000159216,
- Related loop:
chr21:34350000-34375000~~chr21:34775000-34800000,
chr21:34675000-34700000~~chr21:34775000-34800000,
chr21:34775000-34800000~~chr21:34875000-34900000,
chr21:34775000-34800000~~chr21:34975000-35000000,
chr21:34775000-34800000~~chr21:35000000-35025000,
chr21:34775000-34800000~~chr21:35025000-35050000,
chr21:34775000-34800000~~chr21:35350000-35375000,
chr21:34775000-34800000~~chr21:35400000-35425000,
chr21:34775000-34800000~~chr21:35500000-35525000,
chr21:34775000-34800000~~chr21:35725000-35750000,
chr21:34775000-34800000~~chr21:35825000-35850000,
chr21:34775000-34800000~~chr21:35850000-35875000,
chr21:34775000-34800000~~chr21:35925000-35950000,