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Basic information

CohesinDB ID: CDBP00417857

Locus: chr21-34782961-34783349

Data sourse: ENCSR000BLD, GSE67783, ENCSR000BKV, GSE86191, ENCSR000BLY, GSE206145-NatGen2015, ENCSR153HNT, GSE83726, GSE25021, GSE165895

Cell type: MCF-7, H1-hESC, Fibroblast, HCT-116, RH4, SK-N-SH, K-562, HSPC, HFFc6

DNA Sequence of binding site: UCSC hg38

Cohesin category

Peak occupancy ratio: 2% samples have this site.

Cell specificity (0: conserved, 1: cell type specific): 0.900

Subunit: Mau2,SA1,Rad21,SMC1

CTCF binding site: CTCF CTCF motif: False

Genomic location: TES

3D genome

TAD boundary: Boundary

Chromatin hubs: Hub

Hi-C loops: True Hi-ChIP loops: True ChIA-PET loops: True

Compartment: 91% Hi-C samples shows Compartment A

Cis-regulatory elements

Enhancer (Fantom5): non-Enhancer

Super enhancer (SEdb): False

Chromatin annotation: "15_Quies": 65%, "14_ReprPCWk": 14%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).

Co-bound Transcriptional factors: CBFA2T2, BCL6, POU2F2, PGR, EZH2phosphoT487, POU5F1, FOXA2, SS18, ZFX, MAFF, SMAD3, WT1, ZNF205, ERG3, ERG2, ZFHX2, PRDM10, YY1, RELA, RUNX2, MYC, SMARCA4, ZNF184, RAD21, ARNT, HIF1A, HMBOX1, MAX, ZNF143, IKZF1, SUPT5H, MED1, ZNF750, NR3C1, TFAP2C, ESR1, TP53, C11orf30, EGR2, CTCF, JUN, MAFK, KLF1, AR, KLF17, ARID2, ARID1A, FLI1, BRD4, PHIP, MAZ, ZIM3, STAG1, ZNF316

Target gene symbol (double-evidenced CRMs): RUNX1,CLIC6,SMIM11A

Function elements

Human SNPs: .

Number of somatic mutations (coding): 0

Number of somatic mutations (non-coding): 3

Related genes and loops

Related gene: ENSG00000205670, ENSG00000159212, ENSG00000159216,

eachgene

Deatailed information for cohesin site CDBP00417857