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Basic information

CohesinDB ID: CDBP00417859

Locus: chr21-34785778-34786442

Data sourse: GSE86191, GSE206145-NatGen2015, GSE67783, GSE68388

Cell type: Fibroblast, HCT-116, HSPC, HuCC-T1

DNA Sequence of binding site: UCSC hg38

Cohesin category

Peak occupancy ratio: 1% samples have this site.

Cell specificity (0: conserved, 1: cell type specific): 0.956

Subunit: SA1,Rad21,SMC1

CTCF binding site: non-CTCF CTCF motif: False

Genomic location: TES

3D genome

TAD boundary: Boundary

Chromatin hubs: Hub

Hi-C loops: True Hi-ChIP loops: True ChIA-PET loops: True

Compartment: 91% Hi-C samples shows Compartment A

Cis-regulatory elements

Enhancer (Fantom5): non-Enhancer

Super enhancer (SEdb): False

Chromatin annotation: "15_Quies": 64%, "5_TxWk": 23%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).

Co-bound Transcriptional factors: RUNX1, JARID2, ZNF283, SMC1A, ZSCAN5D, ZNF263, PAF1, ZFX, SS18, WT1, ERG3, ERG2, LEO1, ZFHX2, PRDM10, YY1, RELA, SP140, HMGB2, SMC3, SUPT5H, ZNF143, MAF, TEAD1, SUPT16H, ZNF3, OCA2, USF2, RBM22, ARID2, REST, BRD4, TEAD4, STAG1, TFAP2C

Target gene symbol (double-evidenced CRMs): RUNX1,SMIM11A,CLIC6

Function elements

Human SNPs: .

Number of somatic mutations (coding): 0

Number of somatic mutations (non-coding): 1

Related genes and loops

Related gene: ENSG00000205670, ENSG00000159212, ENSG00000159216,

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Deatailed information for cohesin site CDBP00417859