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Basic information

CohesinDB ID: CDBP00417870

Locus: chr21-34803861-34805114

Data sourse: GSE67783, GSE98367, GSE120943, ENCSR153HNT, GSE50893

Cell type: Monocytes, GM2610, K-562, HSPC, Macrophage

DNA Sequence of binding site: UCSC hg38

Cohesin category

Peak occupancy ratio: 1% samples have this site.

Cell specificity (0: conserved, 1: cell type specific): 0.944

Subunit: SA1,SMC1

CTCF binding site: non-CTCF CTCF motif: False

Genomic location: Intragenic

3D genome

TAD boundary: Boundary

Chromatin hubs: Hub

Hi-C loops: True Hi-ChIP loops: True ChIA-PET loops: True

Compartment: 91% Hi-C samples shows Compartment A

Cis-regulatory elements

Enhancer (Fantom5): non-Enhancer

Super enhancer (SEdb): True

Chromatin annotation: "5_TxWk": 40%, "15_Quies": 24%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).

Co-bound Transcriptional factors: MAFG, CEBPA, GTF2B, STAT1, FOXA1, MLLT3, MEF2C, CDK9, LEO1, HOXB13, RELA, ZNF384, RUNX3, SUPT5H, CDK8, CEBPB, TRIM28, C11orf30, RBM22, MAFK, SPI1, IRF1, BRD4, PHIP, ZNF316, EED

Target gene symbol (double-evidenced CRMs): SMIM11A,RCAN1,RUNX1,SETD4,CLIC6

Function elements

Human SNPs: .

Number of somatic mutations (coding): 16

Number of somatic mutations (non-coding): 0

Related genes and loops

Related gene: ENSG00000205670, ENSG00000159200, ENSG00000159212, ENSG00000159216, ENSG00000185917,

eachgene

Deatailed information for cohesin site CDBP00417870