- Basic information
- CohesinDB ID: CDBP00417887
- Locus: chr21-34895350-34895823
-
Data sourse: GSE116344, GSE206145-NatGen2015, ENCSR153HNT
-
Cell type: K-562, Fibroblast, RH4
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 1% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.967
- Subunit: SA1,Rad21
-
CTCF binding site: non-CTCF
CTCF motif: False
- Genomic location: Intragenic
- 3D genome
- TAD boundary: Boundary
- Chromatin hubs: Hub
-
Hi-C loops: True
Hi-ChIP loops: True
ChIA-PET loops: True
- Compartment:
91% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): True
-
Chromatin annotation:
"14_ReprPCWk": 36%,
"15_Quies": 25%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
-
Co-bound Transcriptional factors: POU5F1, ZSCAN5C, STAT1, SUZ12, LEO1, KDM1A, RELA, MEN1, MYC, ARNT, GABPA, IKZF1, RCOR1, TEAD1, KMT2A, CREB1, ZMYM3, EZH2, NCOA1, AR, ZBTB7A, RBM25, BCOR, TEAD4
- Target gene symbol (double-evidenced CRMs): CLIC6,SIM2,SMIM11A,RCAN1,SETD4,RUNX1,ITSN1,ATP5PO,AP000311.1
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 4
- Number of somatic mutations (non-coding): 0
- Related genes and loops
- Related gene:
ENSG00000249209,
ENSG00000205726,
ENSG00000241837,
ENSG00000205670,
ENSG00000159200,
ENSG00000159212,
ENSG00000159216,
ENSG00000185917,
ENSG00000159263,
- Related loop:
chr21:33900000-33925000~~chr21:34875000-34900000,
chr21:34350000-34375000~~chr21:34875000-34900000,
chr21:34500000-34525000~~chr21:34875000-34900000,
chr21:34600000-34625000~~chr21:34875000-34900000,
chr21:34675000-34700000~~chr21:34875000-34900000,
chr21:34725000-34750000~~chr21:34875000-34900000,
chr21:34744530-34746777~~chr21:34887476-34892097,
chr21:34744561-34746765~~chr21:34887508-34892091,
chr21:34744855-34746749~~chr21:34887552-34891083,
chr21:34744866-34746754~~chr21:34887518-34891075,
chr21:34744879-34746754~~chr21:34888325-34891071,
chr21:34750000-34775000~~chr21:34875000-34900000,
chr21:34775000-34800000~~chr21:34875000-34900000,
chr21:34800665-34802895~~chr21:34887508-34892091,
chr21:34800839-34803321~~chr21:34887491-34891013,
chr21:34801023-34802438~~chr21:34887518-34891075,
chr21:34875000-34900000~~chr21:34975000-35000000,
chr21:34875000-34900000~~chr21:35000000-35025000,
chr21:34875000-34900000~~chr21:35025000-35050000,
chr21:34875000-34900000~~chr21:35125000-35150000,
chr21:34875000-34900000~~chr21:35150000-35175000,
chr21:34875000-34900000~~chr21:35175000-35200000,
chr21:34875000-34900000~~chr21:35200000-35225000,
chr21:34875000-34900000~~chr21:35225000-35250000,
chr21:34875000-34900000~~chr21:35250000-35275000,
chr21:34875000-34900000~~chr21:35300000-35325000,
chr21:34875000-34900000~~chr21:35350000-35375000,
chr21:34875000-34900000~~chr21:35375000-35400000,
chr21:34875000-34900000~~chr21:35400000-35425000,
chr21:34875000-34900000~~chr21:35500000-35525000,
chr21:34875000-34900000~~chr21:35575000-35600000,
chr21:34875000-34900000~~chr21:35600000-35625000,
chr21:34875000-34900000~~chr21:35625000-35650000,
chr21:34875000-34900000~~chr21:35825000-35850000,
chr21:34875000-34900000~~chr21:35925000-35950000,
chr21:34875000-34900000~~chr21:35975000-36000000,
chr21:34875000-34900000~~chr21:36025000-36050000,
chr21:34875000-34900000~~chr21:36100000-36125000,
chr21:34875000-34900000~~chr21:36675000-36700000,
chr21:34887476-34892097~~chr21:35399848-35401817,
chr21:34887476-34892097~~chr21:35614293-35617009,
chr21:34887476-34892097~~chr21:35838896-35841159,
chr21:34887491-34891013~~chr21:35399577-35401546,
chr21:34887508-34892091~~chr21:35203103-35206366,
chr21:34887508-34892091~~chr21:35255866-35258344,
chr21:34887508-34892091~~chr21:35399885-35401612,
chr21:34887508-34892091~~chr21:35615361-35617172,
chr21:34887508-34892091~~chr21:35642873-35644084,
chr21:34887508-34892091~~chr21:35839117-35841138,
chr21:34887510-34891018~~chr21:35047687-35050087,
chr21:34887510-34891018~~chr21:35399417-35401599,
chr21:34887510-34891018~~chr21:35615456-35617044,
chr21:34887518-34891075~~chr21:35399881-35401571,
chr21:34887518-34891075~~chr21:35839484-35840994,
chr21:34887552-34891083~~chr21:35205570-35207542,
chr21:34887552-34891083~~chr21:35399904-35401567,
chr21:34887552-34891083~~chr21:35507875-35509392,
chr21:34887552-34891083~~chr21:35839536-35841080,
chr21:34887571-34890954~~chr21:35399686-35401482,
chr21:34888052-34891094~~chr21:35399888-35401573,
chr21:34888113-34891105~~chr21:35399887-35401439,
chr21:34888113-34891105~~chr21:35507813-35509282,
chr21:34888151-34890935~~chr21:35399911-35401339,
chr21:34888151-34890935~~chr21:35507640-35509736,
chr21:34888177-34892032~~chr21:35399380-35401604,
chr21:34888177-34892032~~chr21:35507839-35509185,
chr21:34888177-34892032~~chr21:35615399-35616943,
chr21:34888177-34892032~~chr21:35838708-35841092,
chr21:34888325-34891071~~chr21:35399859-35401454,
chr21:34888362-34892029~~chr21:35399641-35401580,
chr21:34888362-34892029~~chr21:35507701-35509916,
chr21:34888362-34892029~~chr21:35838891-35841138,
chr21:34888802-34891093~~chr21:35399692-35401398,
chr21:34888858-34890919~~chr21:35399665-35401305,
chr21:34889120-34891504~~chr21:35399872-35401634,
chr21:34889120-34891504~~chr21:35507809-35509924,
chr21:34889124-34891177~~chr21:35399927-35401584,
chr21:34889146-34892075~~chr21:35399320-35401617,
chr21:34889149-34891526~~chr21:35048126-35049812,
chr21:34889149-34891526~~chr21:35399613-35401825,
chr21:34889149-34891526~~chr21:35839251-35841748,
chr21:34889184-34892059~~chr21:35399810-35401595,
chr21:34889184-34892059~~chr21:35615365-35617187,
chr21:34889184-34892059~~chr21:35838738-35841127,
chr21:34889188-34892063~~chr21:35047029-35048282,
chr21:34889188-34892063~~chr21:35050481-35052295,
chr21:34889188-34892063~~chr21:35399614-35401619,
chr21:34889188-34892063~~chr21:35839343-35841742,
chr21:34889198-34891559~~chr21:35399887-35401622,
chr21:34889210-34891617~~chr21:35399329-35401604,
chr21:34889215-34891125~~chr21:35399911-35401639,
chr21:34889215-34891125~~chr21:35507798-35509438,
chr21:34889215-34891491~~chr21:35026230-35029706,
chr21:34889215-34891491~~chr21:35050056-35052270,
chr21:34889215-34891491~~chr21:35339729-35341143,
chr21:34889215-34891491~~chr21:35367866-35369303,
chr21:34889215-34891491~~chr21:35399637-35401641,
chr21:34889215-34891491~~chr21:35615343-35617201,
chr21:34889216-34892087~~chr21:35204275-35205597,
chr21:34889220-34892087~~chr21:35398191-35399421,
chr21:34889220-34892087~~chr21:35399738-35401521,
chr21:34889220-34892087~~chr21:35507756-35509525,
chr21:34889223-34891142~~chr21:35048216-35049984,
chr21:34889223-34891142~~chr21:35252255-35253863,
chr21:34889223-34891142~~chr21:35399305-35401597,
chr21:34889223-34891142~~chr21:35839105-35841278,
chr21:34889226-34891333~~chr21:35507750-35509614,
chr21:34889230-34891145~~chr21:35399668-35401583,
chr21:34889230-34891145~~chr21:35507406-35509556,
chr21:34889231-34891534~~chr21:35050273-35052269,
chr21:34889231-34891534~~chr21:35399325-35401608,
chr21:34889242-34892124~~chr21:35399900-35402112,
chr21:34889242-34892124~~chr21:35507767-35509947,
chr21:34889242-34892124~~chr21:35577853-35579865,
chr21:34889251-34892128~~chr21:35374172-35375997,
chr21:34889251-34892128~~chr21:35399352-35402534,
chr21:34889251-34892128~~chr21:35507734-35509545,
chr21:34889251-34892128~~chr21:35838780-35841161,
chr21:34889254-34891157~~chr21:35399838-35401610,
chr21:34889261-34891776~~chr21:35398829-35401607,
chr21:34889261-34891776~~chr21:35507740-35509497,
chr21:34889265-34891088~~chr21:35507802-35509464,
chr21:34889270-34892070~~chr21:35399625-35402389,
chr21:34889270-34892070~~chr21:35507719-35509586,
chr21:34889270-34892070~~chr21:35838715-35841129,
chr21:34889280-34891141~~chr21:35399667-35401542,
chr21:34889280-34892057~~chr21:35507840-35509928,
chr21:34889297-34891513~~chr21:35399678-35401615,
chr21:34889298-34892087~~chr21:35399898-35401583,
chr21:34889298-34892087~~chr21:35507789-35509940,
chr21:34889303-34891098~~chr21:35399841-35401521,
chr21:34889367-34892315~~chr21:35398021-35401583,
chr21:34889367-34892315~~chr21:35507729-35509950,
chr21:34889367-34892315~~chr21:35838730-35841126,
chr21:34889375-34890944~~chr21:35839523-35841115,
chr21:34889427-34892109~~chr21:35046768-35049526,
chr21:34889427-34892109~~chr21:35398212-35401570,
chr21:34889427-34892109~~chr21:35507807-35509535,
chr21:34889427-34892109~~chr21:35614047-35617200,
chr21:34889427-34892109~~chr21:35839090-35841121,
chr21:34889484-34890922~~chr21:35399886-35401254,
chr21:34889494-34891026~~chr21:35399649-35401523,
chr21:34889504-34891012~~chr21:35399885-35401523,
chr21:34889513-34890925~~chr21:35507897-35509157,
chr21:34900000-34925000~~chr21:35025000-35050000,
chr21:34900000-34925000~~chr21:35200000-35225000,
chr21:34900000-34925000~~chr21:35375000-35400000,
chr21:34900000-34925000~~chr21:35400000-35425000,