- Basic information
- CohesinDB ID: CDBP00417897
- Locus: chr21-34922546-34922797
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Data sourse: ENCSR000BLD, GSE105028, GSE72082, ENCSR000BLS
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Cell type: H1-hESC, Hep-G2, H9-hESC
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 1% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.967
- Subunit: Rad21
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CTCF binding site: CTCF
CTCF motif: True
- Genomic location: Intragenic
- 3D genome
- TAD boundary: Boundary
- Chromatin hubs: Hub
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Hi-C loops: True
Hi-ChIP loops: False
ChIA-PET loops: True
- Compartment:
91% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): True
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Chromatin annotation:
"15_Quies": 58%,
"5_TxWk": 13%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: NFIA, PGR, HMG20A, ZNF496, MEIS2, XBP1, FOXA1, LEO1, PBX2, HDGF, ATF3, RUNX3, ATF4, MITF, TEAD1, TRIM28, ELF1, ESR1, USF2, CTCF, JUN, EP300, TRIM24, RAD51, E2F1, ZNF528, FOXA3, KMT2B, GATAD2A, EHMT2, TFAP2C, POU2F2, CHD8, POU5F1, CDK7, TOP2A, MTA2, ZNF317, DUX4, SRF, ERG, PBX1, MYC, HOMEZ, RAD21, GRHL3, GABPA, IKZF1, NFE2, NR2F6, VDR, NR3C1, CEBPB, ZNF750, KMT2A, CREB1, SPI1, INTS13, ZNF644, FLI1, ZIM3, ATF1, RUNX1, BCL6, MAFG, CEBPA, SOX13, ZFX, SMAD3, RARA, NOTCH1, PBX4, ARNT, ATF2, ZNF48, ZEB2, SMAD4, SUPT5H, CDK8, MED1, MYB, SCRT2, ZMYM3, L3MBTL2, USF1, RBM25, ATF7, HNRNPLL, FOXA2, CREM, ZNF692, MEF2C, CDK9, HOXB13, KDM1A, RELA, ZNF148, HIF1A, GATA3, TAL1, MAF1, MAX, SPIB, CEBPG, ZNF592, KLF4, NCOA3, MED, BCL6B, ELF3, BHLHE40, AR, BRD4, JUND, SCRT1
- Target gene symbol (double-evidenced CRMs): RUNX1
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 4
- Number of somatic mutations (non-coding): 0
- Related genes and loops