- Basic information
- CohesinDB ID: CDBP00417901
- Locus: chr21-34930533-34931355
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Data sourse: GSE98367, ENCSR000HPG, GSE206145, GSE206145-NatGen2015, GSE120943, GSE165895
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Cell type: RPE, Fibroblast, Monocytes, IMR-90, Macrophage, HFFc6
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 3% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.933
- Subunit: NIPBL,Rad21,SMC1,SA2,Mau2,SMC3
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CTCF binding site: non-CTCF
CTCF motif: False
- Genomic location: Intragenic
- 3D genome
- TAD boundary: Boundary
- Chromatin hubs: Hub
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Hi-C loops: False
Hi-ChIP loops: False
ChIA-PET loops: True
- Compartment:
91% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): True
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Chromatin annotation:
"15_Quies": 43%,
"5_TxWk": 23%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: FOXA2, SMAD3, YY1, RELA, JUNB, MYC, RUNX2, GATA4, ZKSCAN2, OTX2, TAL1, STAT3, MAX, FOS, NR3C1, TRIM28, MYOD1, SPI1, TAF1, ZNF644, BRD4, SMC3, FOSL2
- Target gene symbol (double-evidenced CRMs): RUNX1
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 12
- Number of somatic mutations (non-coding): 0
- Related genes and loops