- Basic information
- CohesinDB ID: CDBP00417907
- Locus: chr21-34942484-34943548
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Data sourse: GSE67783, GSE98367, ENCSR879KXD, ENCSR153HNT, GSE50893
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Cell type: GM12892, GM2630, GM18505, K-562, HSPC, Macrophage
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 2% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.933
- Subunit: SA1,Rad21,SMC1
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CTCF binding site: non-CTCF
CTCF motif: False
- Genomic location: Intragenic
- 3D genome
- TAD boundary: Boundary
- Chromatin hubs: Hub
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Hi-C loops: False
Hi-ChIP loops: False
ChIA-PET loops: True
- Compartment:
91% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): True
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Chromatin annotation:
"15_Quies": 40%,
"7_Enh": 20%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: RUNX1, POU2F2, SMC1A, HDAC1, MTA3, EBF1, MYCN, SS18, ZFX, MEIS2, XBP1, MEIS1, DUX4, WT1, NFATC1, ZBTB33, NBN, LEO1, PBX2, CDK9, NSD2, ERG, RELA, HDGF, NFKB2, JUNB, MYC, RUNX2, SMARCA4, SETX, NFIC, RUNX3, GRHL3, ARNT, CBFB, BATF3, BATF, MAX, ETV6, SPIB, GATA1, IKZF1, CDK8, RCOR1, ZNF736, LEF1, ARNTL, VDR, MAF, PDX1, GFI1B, STAT5B, TRIM28, KMT2A, MYB, ZNF592, EZH2, TP53, PKNOX1, OCA2, L3MBTL2, MED, NFKB1, EVI1, CTCF, BCL11A, SPI1, TBX21, GATA6, DPF2, ZBTB40, GATA2, IRF4, CREB3, SOX6, NOTCH3, BRD4, HOXA9, TCF3, STAG1, RBPJ, EED
- Target gene symbol (double-evidenced CRMs): RUNX1
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 14
- Number of somatic mutations (non-coding): 0
- Related genes and loops