- Basic information
- CohesinDB ID: CDBP00417909
- Locus: chr21-34945950-34948337
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Data sourse: ENCSR000BLD, GSE104888, ENCSR230ZWH, ENCSR000FAD, GSE72082, ENCSR000BSB, ENCSR000EGW, ENCSR000BLY, GSE105028, GSE121355, GSE103477, GSE25021, ENCSR917QNE, ENCSR000EFJ, GSE143937, ENCSR000BKV, GSE76893, GSE152721, GSE116344, GSE130140, GSE98367, ENCSR879KXD, ENCSR000BLS, ENCSR000ECE, ENCSR000BMY, GSE97394, ENCSR167MTG, GSE110061, GSE129526, ENCSR000HPG, ENCSR054FKH, ENCSR000EDE, ENCSR153HNT, GSE83726, GSE50893, GSE126755
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Cell type: MDM, RH4, GM2610, CUTLL1, Liver, H9-hESC, GM2630, HeLa-S3, IMR-90, K-562, GM18486, H1-hESC, SNYDER, GM18505, GM12878, GM12891, GM2588, SK-N-SH, GM19239, GM19193, Macrophage, HUES64, MCF-7, GM12892, HCT-116, Hep-G2, Neutrophil, HAP1
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 14% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.689
- Subunit: SA1,Rad21,SMC1,SA2,SMC3
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CTCF binding site: CTCF
CTCF motif: False
- Genomic location: Intragenic
- 3D genome
- TAD boundary: Boundary
- Chromatin hubs: Hub
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Hi-C loops: False
Hi-ChIP loops: False
ChIA-PET loops: True
- Compartment:
91% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): True
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Chromatin annotation:
"15_Quies": 43%,
"7_Enh": 21%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: MAFG, FOXA2, MYCN, E2F7, ZFX, WT1, NBN, LEO1, HNRNPK, RELA, HDGF, NOTCH1, SMARCA4, RAD21, SP140, GRHL3, APC, MAX, STAT3, IKZF1, NFE2, MED1, NR3C1, ZNF573, MYB, NFE2L2, PKNOX1, C11orf30, MYOD1, JUN, DPF2, BRD4, JUND, EHMT2, ZNF316
- Target gene symbol (double-evidenced CRMs): RUNX1
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 32
- Number of somatic mutations (non-coding): 0
- Related genes and loops