- Basic information
- CohesinDB ID: CDBP00417911
- Locus: chr21-34951000-34951552
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Data sourse: GSE143937, ENCSR000BKV, ENCSR000FAD, ENCSR000EGW, ENCSR879KXD, GSE68388
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Cell type: K-562, HuCC-T1
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 1% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.978
- Subunit: SMC3,Rad21,SMC1
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CTCF binding site: non-CTCF
CTCF motif: False
- Genomic location: Intragenic
- 3D genome
- TAD boundary: Boundary
- Chromatin hubs: Hub
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Hi-C loops: True
Hi-ChIP loops: False
ChIA-PET loops: True
- Compartment:
91% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): True
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Chromatin annotation:
"15_Quies": 52%,
"5_TxWk": 24%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: FOSL1, MAFG, ZNF316, FOXA2, HDAC1, CBX3, ZFX, MEIS2, MTA2, SMAD3, MAFF, FOXA1, LEO1, UBTF, PBX2, MLL4, TBP, ARID3A, YY1, RELA, IRF2, NEUROD1, ATF3, SMARCA4, RFX1, ARID1B, CHAMP1, RAD21, ZFP36, PROX1, NKX2-1, ZEB2, MGA, SMARCE1, CBFA2T3, MAX, TAL1, GATA1, IKZF1, NFE2, RCOR1, XRCC5, KLF4, CEBPB, ZNF592, GFI1B, SPDEF, TEAD1, CEBPD, SCRT2, KLF6, NFE2L2, TRIM28, TP53, HNF1B, PKNOX1, C11orf30, L3MBTL2, ELF3, T, JUN, USF1, EP300, MAFK, MNT, AR, IRF1, DPF2, HDAC2, REST, E2F6, ZBTB7A, RNF2, BRD4, JUND, TEAD4, TFAP2C
- Target gene symbol (double-evidenced CRMs): RUNX1,SMIM11A
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 6
- Number of somatic mutations (non-coding): 0
- Related genes and loops