- Basic information
- CohesinDB ID: CDBP00417912
- Locus: chr21-34952726-34953061
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Data sourse: GSE206145, ENCSR153HNT, GSE68388
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Cell type: K-562, RPE, HuCC-T1
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 1% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.967
- Subunit: Mau2,SA1,SMC1
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CTCF binding site: non-CTCF
CTCF motif: False
- Genomic location: Intragenic
- 3D genome
- TAD boundary: Boundary
- Chromatin hubs: Hub
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Hi-C loops: True
Hi-ChIP loops: False
ChIA-PET loops: True
- Compartment:
91% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): True
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Chromatin annotation:
"15_Quies": 51%,
"7_Enh": 20%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: RUNX1, GLIS1, ZNF283, NANOG, HDAC1, EBF1, CDK7, ID3, TEAD4, HNF1A, ZBTB17, SMAD3, XBP1, ZBTB48, FOXA1, CDK9, LEO1, ERG, YY1, KDM1A, RELA, NOTCH1, ASCL1, JUNB, ZEB2, MYC, RUNX2, GATA4, SMARCA4, ARID1B, CHD7, ZNF830, ZIC2, PBX4, HIF1A, PROX1, NKX2-1, GATA3, GRHL3, GABPA, HMBOX1, STAT3, MAX, TAL1, SP2, SUPT5H, GATA1, NFE2, SMARCE1, CBFA2T3, RCOR1, IKZF1, KLF4, CEBPB, SP7, NR3C1, TEAD1, TRIM28, MYB, KLF6, KMT2A, ZMYM3, TP53, HNF1B, OCA2, FEZF1, MYOD1, STAT5A, ELF3, BCL11A, SPI1, IRF1, DPF2, GATA2, RBM25, SOX6, RNF2, BRD4, JUND, ZNF528, ZIM3, EHMT2, AHR
- Target gene symbol (double-evidenced CRMs): RUNX1,SMIM11A
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 4
- Number of somatic mutations (non-coding): 0
- Related genes and loops