- Basic information
- CohesinDB ID: CDBP00417918
- Locus: chr21-34962173-34966667
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Data sourse: GSE206145-GSE177045, ENCSR501LQA, ENCSR760NPX, GSE111537, ENCSR330ELC, GSE165895, ENCSR000EFJ, GSE67783, GSE86191, GSE206145-NatGen2015, GSE135093, GSE120943, GSE116344, ENCSR895JMI, GSE98367, ENCSR768DOX, GSE206145, ENCSR981FDC, ENCSR247LSH, ENCSR807WAC, ENCSR620NWG, ENCSR495WGO, ENCSR217ELF, ENCSR853VWZ, ENCSR956LGB, ENCSR944ZCT, ENCSR000HPG, ENCSR676MJK, GSE111913, ENCSR335RKQ, ENCSR537EFT, ENCSR153HNT, GSE68388, GSE126755, ENCSR748MVX
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Cell type: MCF-7, Macrophage, RPE, Fibroblast, HCT-116, Monocytes, RH4, A-549, OCI-AML-3, RT-112, IMR-90, K-562, Neutrophil, HSPC, HuCC-T1, HFFc6
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 16% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.822
- Subunit: NIPBL,SA1,Rad21,SMC1,SA2,Mau2,SMC3
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CTCF binding site: CTCF
CTCF motif: False
- Genomic location: Intragenic
- 3D genome
- TAD boundary: Boundary
- Chromatin hubs: Hub
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Hi-C loops: True
Hi-ChIP loops: False
ChIA-PET loops: True
- Compartment:
91% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): Enhancer
- Super enhancer (SEdb): True
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Chromatin annotation:
"7_Enh": 23%,
"5_TxWk": 21%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: LEO1, SMARCA4
- Target gene symbol (double-evidenced CRMs): RUNX1,SMIM11A
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 38
- Number of somatic mutations (non-coding): 0
- Related genes and loops