- Basic information
- CohesinDB ID: CDBP00417938
- Locus: chr21-35017299-35017798
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Data sourse: GSE116344, ENCSR153HNT
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Cell type: K-562, RH4
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 0% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.978
- Subunit: SA1,Rad21
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CTCF binding site: non-CTCF
CTCF motif: False
- Genomic location: Intragenic
- 3D genome
- TAD boundary: Boundary
- Chromatin hubs: Hub
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Hi-C loops: True
Hi-ChIP loops: False
ChIA-PET loops: True
- Compartment:
84% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): True
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Chromatin annotation:
"15_Quies": 43%,
"5_TxWk": 24%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: ZNF468, NFIA, FOSL1, TRIM25, FOXO1, HMG20A, NME2, MEIS2, HNF1A, XBP1, FOXA1, RBFOX2, PBX2, LEO1, RXRB, ZFHX2, KDM3A, TFAP4, HDGF, TSC22D4, MEN1, ATF3, THRB, NFIC, ZFP64, THAP1, HNRNPUL1, RUNX3, ATF4, MXD4, MECOM, SMARCE1, ZSCAN4, TP63, MITF, CDX2, MAF, KLF5, ELF1, TRIM28, TEAD1, KLF6, ETV1, NFE2L2, KLF10, LMO2, RCOR2, HNF1B, OCA2, ESR1, HDAC8, JUN, TCF12, CTCF, EP300, BAF155, LMO1, GATA6, SOX5, DPF2, DMAP1, E2F6, TRIM24, SOX6, CREB3, DDX20, ZNF677, TEAD4, FOXA3, ZNF175, GATAD2A, PDX1, TFAP2C, EED, RBPJ, GLIS1, MLX, POU2F2, BRD1, ZNF263, MYCN, POU5F1, ID3, TOP2A, CTBP1, MTA2, ZBTB48, ZSCAN5A, ELK4, STAT1, ZNF205, SRF, GATAD1, SAP130, ERG2, ARID3A, HNF4G, ERG, HOXC5, PAX6, SMARCC2, ETS1, MYC, EZH1, SMARCA4, ONECUT1, ARID1B, RAD21, HOMEZ, GRHL3, PROX1, NKX2-1, RXRA, GABPA, STAT3, XRCC5, ZNF614, NKX3-1, IKZF1, RCOR1, NFE2, NR2F6, MIER3, ZNF750, CEBPB, ESRRA, NR3C1, KMT2A, CREB1, CCAR2, TBL1XR1, EZH2, GRHL2, ZNF652, GABPB1, ZHX2, SPI1, MIXL1, EHF, TFE3, IRF1, HDAC2, GATA2, ZNF644, MXD3, DRAP1, NR2C2, ZGPAT, NFIL3, ATF1, ETV5, RUNX1, THAP11, CIITA, MAFG, BCL6, HDAC1, CEBPA, LDB1, CRY1, NKX2-2, ZFX, SOX13, SMC1A, EZH2phosphoT487, SMAD3, ERG3, SP5, SMARCC1, RARA, CREBBP, NOTCH1, PRPF4, NFYC, RUNX2, CDK6, GATA4, PBX4, DAXX, ELK1, ZNF48, PRDM9, ZEB2, HMBOX1, SMAD4, CBFA2T3, FOXM1, ETV6, SUPT5H, FOS, MAFB, HMGXB4, PBX3, MED1, GMEB1, ZEB1, TEAD3, CEBPD, MYB, ZNF264, ZMYM3, U2AF1, TERF1, ZNF3, NCOA1, L3MBTL2, EVI1, STAT5A, MAFK, BCL11A, TFAP2A, SP1, NR4A1, HNF4A, IKZF5, REST, ARID1A, ARID2, CCNT2, RBM25, ATF7, ZHX1, ASH2L, POU2F3, BCOR, FOXP1, TCF3, SMC3, NCOR2, STAG1, ETV4, SKI, CBFA2T2, PPARG, FOXA2, MTA3, TBL1X, CREM, NFATC1, MIER2, MAFF, WT1, TCF7, ZNF823, CDK9, HOXB13, ZNF580, BCL3, KDM1A, YY1, RELA, JUNB, NEUROD1, SP140, ZIC2, HIF1A, TCF4, GATA3, BATF, TAL1, MAX, SPIB, GATA1, KLF4, ZNF592, ZFP69B, CEBPG, NR2F2, GFI1B, BCL11B, NR2F1, TCF7L2, NEUROG2, TP53, PKNOX1, MED, MYOD1, EGR2, ELF3, PHF5A, KAT8, BCLAF1, TBX21, NFKBIZ, AR, PAX3-FOXO1, ARID4B, BHLHE40, RXR, EGR1, ZBTB26, RNF2, NOTCH3, JUND, ILF3, BRD4, NCOR1, HSF1, MAZ, CUX1, AHR, FOSL2
- Target gene symbol (double-evidenced CRMs): SMIM11A,RUNX1
- Function elements
- Human SNPs: Neutrophil_percentage_of_granulocytes
- Number of somatic mutations (coding): 4
- Number of somatic mutations (non-coding): 0
- Related genes and loops