- Basic information
- CohesinDB ID: CDBP00417949
- Locus: chr21-35064686-35065132
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Data sourse: GSE138405, GSE206145-NatGen2015
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Cell type: Hela-Kyoto, Fibroblast
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 0% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.978
- Subunit: Rad21,SA2
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CTCF binding site: non-CTCF
CTCF motif: False
- Genomic location: Intergenic
- 3D genome
- TAD boundary: Boundary
- Chromatin hubs: Hub
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Hi-C loops: True
Hi-ChIP loops: True
ChIA-PET loops: True
- Compartment:
84% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): True
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Chromatin annotation:
"15_Quies": 75%,
"14_ReprPCWk": 16%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: NME2, XBP1, FOXA1, BMI1, RUNX3, CHD7, ZNF444, ZSCAN4, TP63, CDC5L, TEAD1, ZNF217, ESR1, HNF1B, TP73, JUN, EP300, GATA6, DPF2, ZNF410, TFAP2C, CHD8, MYCN, CTBP1, ZSCAN21, DUX4, SRF, DDX5, ERG, ZBTB21, ASCL1, NFKB2, ONECUT1, MYC, EZH1, RAD21, LHX2, GRHL3, RXRA, GABPA, STAT3, RCOR1, ZNF750, ESRRA, NR3C1, TRPS1, EHF, IRF1, HDAC2, GATA2, GATAD2B, AHRR, SMC1A, HDAC1, SIN3A, ZFX, SMAD3, ZBTB2, CREBBP, RUNX2, GATA4, ARNT, FOS, PIAS1, SP1, NIPBL, HNF4A, REST, CTBP2, SMC3, STAG2, FOXA2, WT1, HOXB13, KDM1A, RELA, JUNB, HIF1A, GATA3, MAX, GATA1, KLF4, NR2F2, TCF7L2, NR2F1, TP53, NFKB1, MYOD1, BRD2, ELF3, TBX21, AR, RXR, HSF1, BRD4, AHR
- Target gene symbol (double-evidenced CRMs): .
- Function elements
- Human SNPs: Eosinophil_percentage_of_white_cells
- Number of somatic mutations (coding): 0
- Number of somatic mutations (non-coding): 1
- Related genes and loops