- Basic information
- CohesinDB ID: CDBP00417964
- Locus: chr21-35097173-35097679
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Data sourse: GSE206145-NatGen2015, GSE98367
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Cell type: Fibroblast, Macrophage
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 1% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.978
- Subunit: Mau2,SMC1
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CTCF binding site: non-CTCF
CTCF motif: False
- Genomic location: Intergenic
- 3D genome
- TAD boundary: non-Boundary
- Chromatin hubs: Hub
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Hi-C loops: False
Hi-ChIP loops: False
ChIA-PET loops: True
- Compartment:
84% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): True
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Chromatin annotation:
"15_Quies": 83%,
"14_ReprPCWk": 6%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: FOXO1, FOSL1, PGR, NME2, FOXA1, PBX2, HDGF, RUNX3, PRDM1, SMARCE1, PAX5, TP63, ZNF736, MAF, DPF2, PAX8, TRIM24, IRF4, TEAD4, PDX1, POU5F1, STAT1, HNF4G, MYC, SMARCA4, ARID1B, GRHL3, BATF3, STAT3, XRCC5, IKZF1, NFE2, RCOR1, NR2F6, VDR, NR3C1, CEBPB, STAT5B, ZNF565, SPI1, HES1, HDAC2, GATA2, ZNF644, SMARCA5, SMC1A, CBX1, HDAC1, LDB1, SOX13, PCBP2, GATA4, ARNT, ZEB2, CBFA2T3, FOS, CDK8, MED1, MYB, ZMYM3, L3MBTL2, STAT5A, MAFK, BCL11A, SP1, NR4A1, HNF4A, RBM25, POU2F3, BCOR, CBX3, FOXA2, MAFF, MEF2C, KDM1A, ZNF19, RELA, JUNB, ZFP36, TCF4, GATA3, MAX, GATA1, MTA1, ZNF143, NR2F2, NR2F1, TP53, TBX21, AR, ZBTB40, EGLN2, EGR1, BRD4, ZNF24, ADNP, FOSL2
- Target gene symbol (double-evidenced CRMs): .
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 0
- Number of somatic mutations (non-coding): 0
- Related genes and loops