- Basic information
- CohesinDB ID: CDBP00417965
- Locus: chr21-35102044-35103499
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Data sourse: ENCSR230ZWH, ENCSR000BKV, GSE86191, GSE138405, GSE98367, ENCSR000HPG, GSE111913, ENCSR879KXD, GSE62063, GSE50893, GSE120943, ENCSR153HNT, GSE83726, GSE73207, GSE111537, GSE116344, GSE126755, GSE55407
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Cell type: Hela-Kyoto, HCT-116, Monocytes, RH4, TF-1, OCI-AML-3, GM19238, RT-112, IMR-90, K-562, Liver, Neutrophil, THP-1, Macrophage, Ramos
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 5% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.833
- Subunit: NIPBL,SA1,Rad21,SMC1,SA2,SMC3
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CTCF binding site: non-CTCF
CTCF motif: False
- Genomic location: Intergenic
- 3D genome
- TAD boundary: non-Boundary
- Chromatin hubs: Hub
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Hi-C loops: True
Hi-ChIP loops: False
ChIA-PET loops: True
- Compartment:
84% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): True
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Chromatin annotation:
"15_Quies": 51%,
"7_Enh": 26%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: FOXO1, HMG20A, MEIS2, XBP1, KDM4B, FOXA1, SUZ12, PBX2, RXRB, TFAP4, HDGF, LYL1, CHD7, ZNF429, MECOM, SMARCE1, JMJD1C, MAF, ELF1, TRIM28, ETV1, LMO2, ESR1, MLL, SMAD5, OCA2, HDAC8, CTCF, TCF12, EP300, E4F1, ARID5B, LMO1, SOX5, DPF2, SOX4, E2F6, SOX6, CREB3, E2F4, E2F1, TEAD4, KMT2B, FOXA3, GATAD2A, EHMT2, EED, ZSCAN5D, MYCN, TOP2A, ID3, RUNX1T1, CTBP1, MTA2, ZBTB48, STAT1, MLLT3, NBN, TBP, ERG, PBX1, SMARCC2, MYC, EZH1, SMARCA4, ARID1B, RAD21, FOXK2, GABPA, XRCC5, IKZF1, RCOR1, LEF1, NR2F6, VDR, NR3C1, CEBPB, KMT2A, CREB1, GRHL2, GABPB1, PHF8, SPI1, HDAC2, GATA2, INTS13, ZNF644, FLI1, NFIL3, ATF1, RUNX1, BCL6, SMC1A, HDAC1, CEBPA, SOX13, ZFX, ERG3, NSD2, RARA, ZNF384, CREBBP, GATA4, ARNT, ZEB2, HMBOX1, SMAD4, CBFA2T3, ETV6, NR2C1, CDK8, CEBPD, MYB, SCRT2, PIAS1, VEZF1, L3MBTL2, EVI1, STAT5A, SP1, BCL11A, HNF4A, NR4A1, REST, ZBTB7A, ATF7, HNRNPLL, TCF3, BCOR, SMC3, STAG1, MLLT1, SKI, MEF2B, FOXA2, CBX3, CREM, MTA3, TBL1X, E2F8, FOXF1, MEF2C, TCF7, CDK9, HOXB13, KDM1A, ZNF589, RELA, YY1, TCF4, BHLHE22, GATA3, MGA, TAL1, MAX, SPIB, GATA1, ZNF143, PLAG1, TLE3, ZNF592, BCL11B, NR2F2, NR2F1, TCF7L2, KDM5B, NEUROG2, PKNOX1, MYOD1, ELF3, BHLHE40, AR, TAF1, ZBTB16, ZBTB40, ZBTB26, NCOR1, RNF2, SCRT1, JUND, BRD4, MYNN, MAZ, ZNF24
- Target gene symbol (double-evidenced CRMs): SMIM11A,RUNX1
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 0
- Number of somatic mutations (non-coding): 0
- Related genes and loops