- Basic information
- CohesinDB ID: CDBP00417968
- Locus: chr21-35111512-35111903
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Data sourse: GSE101921, GSE85526, GSE68388
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Cell type: HMEC, HuCC-T1, HEKn
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 1% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.967
- Subunit: SA2,SMC1
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CTCF binding site: non-CTCF
CTCF motif: False
- Genomic location: Intergenic
- 3D genome
- TAD boundary: non-Boundary
- Chromatin hubs: Hub
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Hi-C loops: True
Hi-ChIP loops: False
ChIA-PET loops: True
- Compartment:
84% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): True
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Chromatin annotation:
"15_Quies": 84%,
"14_ReprPCWk": 8%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: FOSL1, MEIS2, FOXA1, PBX2, HDGF, ATF3, CHD7, CDX2, MAF, ZNF629, TEAD1, TRIM28, ETV1, SNAI2, NFE2L2, LMO2, ESR1, USF2, JUN, CTCF, TCF12, E4F1, DPF2, ZNF92, EHMT2, TFAP2C, TOP2A, ID3, ZNF205, ARID3A, HIC1, HOXC5, ERG, ASCL1, SMARCA4, RAD21, PROX1, GABPA, STAT3, NFE2, RCOR1, NR2F6, CEBPB, FEZF1, SPI1, GATA2, INTS13, FLI1, ATF1, RUNX1, SMC1A, POU4F2, SMAD3, ZNF35, RUNX2, GATA4, ARNT, PBX4, DAXX, ATF2, FOS, CDK8, ZEB1, TERF1, C11orf30, SETDB1, MAFK, BCL11A, POU2F3, TCF3, SMC3, STAG2, PPARG, CBX3, FOXA2, CREM, MEIS1, HOXB13, KDM1A, YY1, RELA, JUNB, AHR, ZNF449, CEBPG, KLF4, ZNF592, TP53, MYOD1, ELF3, BRD2, AR, EGR1, JUND, BRD4, ZNF316, FOSL2
- Target gene symbol (double-evidenced CRMs): RUNX1,SMIM11A
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 0
- Number of somatic mutations (non-coding): 0
- Related genes and loops